In the realm of fine chemicals and research reagents, precise identification and understanding of chemical properties are crucial for successful scientific endeavors. CAS Registry Number (CAS RN) is a unique numerical identifier assigned to every chemical substance described in the public literature. For chemists involved in peptide synthesis, understanding the specifications and applications of compounds like 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one, identified by CAS Number 28230-32-2, is essential. This article serves as a guide to this important chemical, often referred to by its acronym HOOBT.

3-Hydroxy-1,2,3-benzotriazin-4(3H)-one (CAS 28230-32-2) is a heterocyclic organic compound primarily utilized as an additive in peptide synthesis. Its chemical structure, featuring a benzotriazine ring system with hydroxyl and keto functionalities, lends itself to specific reaction chemistry. Typically appearing as a white to off-white crystalline powder, it boasts a high purity level, often specified at 99% by HPLC, ensuring its suitability for demanding research applications. When you need to buy CAS 28230-32-2, it's important to verify these specifications.

The primary application of HOOBT is its role in facilitating and improving peptide bond formation, particularly when employing carbodiimide coupling reagents such as DCC (Dicyclohexylcarbodiimide). In these reactions, HOOBT acts as a racemization suppressor. By forming a stable activated ester intermediate, it prevents the formation of the oxazolone intermediate, which is the common culprit behind stereochemical loss (racemization) during peptide coupling. This makes it an invaluable reagent for researchers aiming to synthesize peptides with high enantiomeric purity. Therefore, understanding its function is key to deciding when to purchase HOOBT.

For procurement professionals and researchers, identifying a reliable manufacturer or supplier for CAS 28230-32-2 is critical. Many high-quality sources for this reagent are available, with numerous companies specializing in chemical intermediates, including those based in China. When seeking to buy this chemical, consider factors such as product purity, consistency, packaging options, and competitive pricing. Many suppliers offer detailed product information, including Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS), which are vital for quality assurance and safe handling.

The economic aspect of acquiring chemical reagents is also significant. The price of HOOBT can vary depending on the supplier, quantity, and market conditions. By comparing offers from multiple vendors, particularly from established chemical distributors and manufacturers, you can secure this essential reagent at the best possible value. Whether you are conducting small-scale laboratory research or large-scale production, a strategic procurement approach will ensure you have access to high-quality CAS 28230-32-2 when you need it.

In summary, 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one (CAS 28230-32-2) is a critical reagent for peptide synthesis, known for its ability to suppress racemization and improve yields. By understanding its properties and sourcing it from reputable manufacturers and suppliers, researchers can ensure the success and accuracy of their synthetic projects.