1-(Mesitylene-2-sulfonyl)-3-nitro-1,2,4-triazole, widely known as MSNT (CAS 74257-00-4), is a chemical compound that has garnered significant attention in the fields of chemistry and biotechnology due to its efficacy as a condensing reagent. NINGBO INNO PHARMCHEM CO.,LTD., a prominent 1-(Mesitylene-2-sulfonyl)-3-nitro-1,2,4-triazole manufacturer in China, offers a detailed look into the properties, synthesis, and industrial applications of this crucial chemical intermediate.

MSNT possesses a molecular formula of C11H12N4O4S and a molecular weight of 296.30 g/mol. Its typical appearance is an off-white to pale yellow crystalline powder, with a high purity level of at least 98.0% confirmed by HPLC. Key physical properties include a melting point range of 134-139°C, density of 1.51 g/cm³, and a boiling point of approximately 533.4°C. These characteristics underscore its stability and suitability for a range of chemical processes, including those requiring specific temperature controls.

The synthesis of MSNT involves the reaction between mesitylene-2-sulfonyl chloride and 3-nitro-1,2,4-triazole. This process requires precise control over reaction conditions to ensure high yield and purity. NINGBO INNO PHARMCHEM CO.,LTD. has optimized these synthesis methods to produce MSNT that consistently meets factory standards, with assay results often reaching 99.4% and minimal loss on drying (typically below 0.5%). Such quality benchmarks are essential for its primary application as a condensing reagent in the synthesis of oligonucleotides, a vital process in molecular biology and genetic research.

Beyond oligonucleotide synthesis, MSNT's utility as a chemical coupling reagent makes it valuable in various organic synthesis pathways. Its application as a chemical intermediate supports the development of new materials and pharmaceutical compounds. For businesses seeking a reliable MSNT supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. provides not only a high-quality product but also expertise in handling and customization. The company's commitment to research and development ensures that their MSNT offerings remain at the forefront of chemical innovation, catering to the evolving needs of the scientific community and industry.

Safety in handling MSNT is also a critical consideration. It is classified under GHS07, indicating potential skin, eye, and respiratory irritation. Proper protective equipment and ventilation are recommended. As a responsible 1-(Mesitylene-2-sulfonyl)-3-nitro-1,2,4-triazole supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. provides comprehensive safety data sheets to ensure safe usage. With its broad applicability and consistent quality, MSNT remains an indispensable reagent for numerous chemical applications.