For any chemist or industrial user working with chemical compounds, a thorough understanding of their properties and safe handling procedures is indispensable. 1-Bromo-4,5-difluoro-2-nitrobenzene, identified by CAS number 321-17-5, is a chemical intermediate with specific characteristics that dictate its use and require careful management. This article provides insights into its key properties and essential safety considerations.

Physical and Chemical Properties

1-Bromo-4,5-difluoro-2-nitrobenzene typically presents as a yellow liquid. Its molecular formula is C6H2BrF2NO2, with a molecular weight of approximately 237.99 g/mol. The compound possesses a boiling point of around 72-74 °C at 4 Torr, indicating its volatility under reduced pressure. The density is approximately 1.890±0.06 g/cm3. These properties are vital for researchers and manufacturers when designing reaction conditions, purification methods, and storage protocols. For instance, its liquid state at room temperature and specific boiling point range influence its handling and purification via distillation.

Safety Information and Handling Precautions

According to the Globally Harmonized System (GHS), 1-Bromo-4,5-difluoro-2-nitrobenzene is classified with specific hazard statements. Commonly indicated hazards include skin irritation (H315), serious eye irritation (H319), and potential respiratory irritation (H335). Consequently, appropriate precautionary statements must be followed during handling. These typically include:

  • P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P264: Wash hands and exposed skin thoroughly after handling.
  • P271: Use only outdoors or in a well-ventilated area.
  • P280: Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352: IF ON SKIN: Wash with plenty of water.
  • P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P312: Call a POISON CENTER/doctor if you feel unwell.
  • P362: Take off contaminated clothing.
  • P403+P233: Store in a well-ventilated place. Keep container tightly closed.
  • P405: Store locked up.
  • P501: Dispose of contents/container in accordance with local/regional/national/international regulations.

It is essential to always consult the latest Safety Data Sheet (SDS) provided by the supplier for comprehensive and up-to-date safety information. When purchasing, ensure you buy from a supplier that provides comprehensive safety data.

Where to Purchase and Obtain Support

For reliable sourcing of 1-Bromo-4,5-difluoro-2-nitrobenzene (CAS 321-17-5), partnering with a reputable manufacturer is key. We, as a leading chemical supplier, ensure that our product meets high-quality standards and that comprehensive safety information is readily available. When you need to buy this intermediate, contact our sales team for pricing and availability. We are dedicated to providing excellent customer service and ensuring you have all the necessary information for safe and effective use.