Fmoc-Hyp(tBu)-OH: A Cornerstone for Peptide Synthesis Researchers
For scientists engaged in the intricate field of peptide synthesis, having access to high-quality reagents is non-negotiable. Fmoc-Hyp(tBu)-OH (CAS 122996-47-8) has emerged as a cornerstone building block, enabling the precise construction of complex peptide sequences. This article aims to illuminate the importance of this compound and the advantages of sourcing it from a trusted manufacturer like NINGBO INNO PHARMCHEM CO.,LTD.
Fmoc-Hyp(tBu)-OH is a derivative of L-hydroxyproline, a non-proteinogenic amino acid that plays a crucial role in protein structure and function. In peptide synthesis, particularly within the widely adopted Fmoc solid-phase peptide synthesis (SPPS) methodology, this protected amino acid is indispensable. The Fmoc group provides a base-labile protecting group for the N-terminus, while the tert-butyl (tBu) group safeguards the hydroxyl function of hydroxyproline. This strategic protection allows for selective deprotection and coupling steps, ensuring the linear assembly of amino acids into the desired peptide chain.
The reliable incorporation of Fmoc-Hyp(tBu)-OH into peptide sequences contributes significantly to the overall structural integrity and bioactivity of the final peptide. Researchers often rely on this specific building block to introduce conformational constraints or to mimic specific structures found in natural proteins. Its purity is paramount; impurities can lead to a cascade of errors, resulting in low-yield, impure peptide products that require extensive purification, thus increasing costs and time.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting the research community by providing Fmoc-Hyp(tBu)-OH with exceptional purity levels (typically u226598%). As a leading supplier from China, we understand the demands of peptide synthesis and the need for consistent, high-quality reagents. Our manufacturing processes are optimized to ensure that each batch of Fmoc-Hyp(tBu)-OH meets stringent specifications, making it a dependable choice for academic and industrial laboratories.
The price of Fmoc-Hyp(tBu)-OH can vary, but investing in a high-purity product from a reputable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ultimately proves more cost-effective by minimizing synthesis failures and purification challenges. We aim to make essential research materials accessible without compromising on quality, offering competitive pricing and reliable global shipping.
In essence, Fmoc-Hyp(tBu)-OH is more than just a chemical reagent; it's a critical enabler of scientific progress in peptide research. By partnering with NINGBO INNO PHARMCHEM CO.,LTD., researchers can confidently access this key building block, ensuring the success and efficiency of their vital work in developing new therapeutics and understanding complex biological processes.
Fmoc-Hyp(tBu)-OH is a derivative of L-hydroxyproline, a non-proteinogenic amino acid that plays a crucial role in protein structure and function. In peptide synthesis, particularly within the widely adopted Fmoc solid-phase peptide synthesis (SPPS) methodology, this protected amino acid is indispensable. The Fmoc group provides a base-labile protecting group for the N-terminus, while the tert-butyl (tBu) group safeguards the hydroxyl function of hydroxyproline. This strategic protection allows for selective deprotection and coupling steps, ensuring the linear assembly of amino acids into the desired peptide chain.
The reliable incorporation of Fmoc-Hyp(tBu)-OH into peptide sequences contributes significantly to the overall structural integrity and bioactivity of the final peptide. Researchers often rely on this specific building block to introduce conformational constraints or to mimic specific structures found in natural proteins. Its purity is paramount; impurities can lead to a cascade of errors, resulting in low-yield, impure peptide products that require extensive purification, thus increasing costs and time.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting the research community by providing Fmoc-Hyp(tBu)-OH with exceptional purity levels (typically u226598%). As a leading supplier from China, we understand the demands of peptide synthesis and the need for consistent, high-quality reagents. Our manufacturing processes are optimized to ensure that each batch of Fmoc-Hyp(tBu)-OH meets stringent specifications, making it a dependable choice for academic and industrial laboratories.
The price of Fmoc-Hyp(tBu)-OH can vary, but investing in a high-purity product from a reputable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ultimately proves more cost-effective by minimizing synthesis failures and purification challenges. We aim to make essential research materials accessible without compromising on quality, offering competitive pricing and reliable global shipping.
In essence, Fmoc-Hyp(tBu)-OH is more than just a chemical reagent; it's a critical enabler of scientific progress in peptide research. By partnering with NINGBO INNO PHARMCHEM CO.,LTD., researchers can confidently access this key building block, ensuring the success and efficiency of their vital work in developing new therapeutics and understanding complex biological processes.
Perspectives & Insights
Agile Reader One
“The Fmoc group provides a base-labile protecting group for the N-terminus, while the tert-butyl (tBu) group safeguards the hydroxyl function of hydroxyproline.”
Logic Vision Labs
“This strategic protection allows for selective deprotection and coupling steps, ensuring the linear assembly of amino acids into the desired peptide chain.”
Molecule Origin 88
“The reliable incorporation of Fmoc-Hyp(tBu)-OH into peptide sequences contributes significantly to the overall structural integrity and bioactivity of the final peptide.”