For any successful peptide synthesis or drug discovery project, the quality of the starting materials is non-negotiable. Fmoc-Pro-OH, a crucial Fmoc-protected amino acid with CAS number 71989-31-6, is one such vital reagent. Sourcing high-quality Fmoc-Pro-OH from reliable suppliers is essential for ensuring the integrity and efficiency of your research and development processes.

When looking to buy Fmoc-Pro-OH, it’s important to consider several factors. Firstly, the purity of the compound is paramount. Typically, for peptide synthesis applications, a purity of 99% or higher is required. This is often verified through analytical techniques like High-Performance Liquid Chromatography (HPLC). Suppliers should readily provide Certificates of Analysis (CoA) that detail the purity, physical properties, and spectral data of their Fmoc-Pro-OH batches.

The second consideration is the supplier's reputation and reliability. Established manufacturers and distributors specializing in peptide synthesis reagents and amino acid derivatives are generally preferred. These companies often have rigorous quality control measures in place and a proven track record of consistent product delivery. Looking for suppliers based in regions known for chemical manufacturing, such as China, can also offer competitive pricing for bulk orders of Fmoc-Pro-OH.

Packaging and storage conditions are also important. Fmoc-Pro-OH is typically supplied as a solid powder and should be stored under recommended conditions (often refrigerated, like at 4°C or -20°C) to maintain its stability and prevent degradation. Reliable suppliers will provide clear guidance on storage and handling.

The price of Fmoc-Pro-OH can vary based on the quantity, purity, and supplier. For researchers working on a budget, comparing prices from different vendors for specific pack sizes (e.g., 1g, 5g, 25g, 100g, 500g) is a practical step. However, it's crucial to balance cost with quality and assurance of supply.

In summary, sourcing high-quality Fmoc-Pro-OH involves careful selection of suppliers who can guarantee purity, provide necessary documentation, and offer reliable delivery. By prioritizing these aspects, researchers and chemists can secure the essential amino acid derivative needed for their advanced peptide synthesis and drug discovery initiatives.