Why Choose Fmoc-Val-OSu? Purity and Performance in Peptide Chemistry
In the demanding field of peptide synthesis, the quality of your reagents directly impacts the outcome of your research. Fmoc-Val-OSu, identified by CAS number 130878-68-1, is a cornerstone reagent that offers significant advantages in terms of purity and performance. When researchers decide to buy Fmoc-Val-OSu, they are seeking a reliable partner in their quest for accurately synthesized peptides, often turning to established manufacturers and suppliers in China.
The primary advantage of using Fmoc-Val-OSu lies in its Fmoc protection strategy. This method is celebrated for its mild deprotection conditions, typically involving a base like piperidine, which are orthogonal to many other protecting groups used in peptide synthesis. This orthogonality is vital for constructing complex peptide sequences with high fidelity. The N-hydroxysuccinimide (NHS) ester component of Fmoc-Val-OSu activates the carboxyl group of valine, making it highly reactive towards the amine terminus of a growing peptide chain. This efficient activation facilitates rapid coupling, thereby shortening synthesis times and minimizing the risk of racemization.
Purity is a critical parameter when sourcing Fmoc-Val-OSu. Reputable suppliers ensure that their product meets stringent purity standards, often exceeding 99% as confirmed by High-Performance Liquid Chromatography (HPLC). This high purity is essential to prevent the incorporation of impurities into the peptide chain, which could lead to erroneous results in downstream applications such as protein structure analysis or drug screening. Many suppliers, especially those in China, provide detailed Certificates of Analysis (CoA) that document the purity and other key specifications, offering assurance to researchers.
The chemical formula C24H24N2O6 and molecular weight of 436.45 g/mol are standard characteristics of Fmoc-Val-OSu. Understanding these properties helps in accurate weighing and stoichiometric calculations during the synthesis process. For researchers looking for cost-effective solutions without compromising on quality, sourcing Fmoc-Val-OSu from reliable Chinese manufacturers presents a viable option.
In conclusion, the choice of Fmoc-Val-OSu is a strategic decision for anyone involved in peptide synthesis or proteomics. Its combination of Fmoc protection and NHS ester activation offers efficiency and reliability. Prioritizing high purity and sourcing from trusted suppliers are key steps to ensuring the success and integrity of your research projects.
The primary advantage of using Fmoc-Val-OSu lies in its Fmoc protection strategy. This method is celebrated for its mild deprotection conditions, typically involving a base like piperidine, which are orthogonal to many other protecting groups used in peptide synthesis. This orthogonality is vital for constructing complex peptide sequences with high fidelity. The N-hydroxysuccinimide (NHS) ester component of Fmoc-Val-OSu activates the carboxyl group of valine, making it highly reactive towards the amine terminus of a growing peptide chain. This efficient activation facilitates rapid coupling, thereby shortening synthesis times and minimizing the risk of racemization.
Purity is a critical parameter when sourcing Fmoc-Val-OSu. Reputable suppliers ensure that their product meets stringent purity standards, often exceeding 99% as confirmed by High-Performance Liquid Chromatography (HPLC). This high purity is essential to prevent the incorporation of impurities into the peptide chain, which could lead to erroneous results in downstream applications such as protein structure analysis or drug screening. Many suppliers, especially those in China, provide detailed Certificates of Analysis (CoA) that document the purity and other key specifications, offering assurance to researchers.
The chemical formula C24H24N2O6 and molecular weight of 436.45 g/mol are standard characteristics of Fmoc-Val-OSu. Understanding these properties helps in accurate weighing and stoichiometric calculations during the synthesis process. For researchers looking for cost-effective solutions without compromising on quality, sourcing Fmoc-Val-OSu from reliable Chinese manufacturers presents a viable option.
In conclusion, the choice of Fmoc-Val-OSu is a strategic decision for anyone involved in peptide synthesis or proteomics. Its combination of Fmoc protection and NHS ester activation offers efficiency and reliability. Prioritizing high purity and sourcing from trusted suppliers are key steps to ensuring the success and integrity of your research projects.
Perspectives & Insights
Chem Catalyst Pro
“Its combination of Fmoc protection and NHS ester activation offers efficiency and reliability.”
Agile Thinker 7
“Prioritizing high purity and sourcing from trusted suppliers are key steps to ensuring the success and integrity of your research projects.”
Logic Spark 24
“In the demanding field of peptide synthesis, the quality of your reagents directly impacts the outcome of your research.”