Acetals are a fundamental class of organic compounds, prized in synthetic chemistry for their ability to protect carbonyl groups and their unique reactivity. Among these, 1,1,2-Trimethoxyethane, also known as Methoxyacetaldehyde Dimethyl Acetal (CAS: 24332-20-5), stands out as a particularly versatile building block. Its structure, characterized by three methoxy groups attached to an ethane backbone, grants it specific properties that are highly valued in various synthesis pathways.

The Chemical Nature of 1,1,2-Trimethoxyethane

As a derivative of methoxyacetaldehyde, 1,1,2-Trimethoxyethane functions as a dimethyl acetal. This acetal functionality is key to its utility. Carbonyl groups (aldehydes and ketones) are highly reactive, and acetals serve as stable protecting groups that can be introduced and later removed under specific conditions, typically acidic hydrolysis. This allows chemists to perform reactions on other parts of a molecule without affecting the carbonyl group, a cornerstone strategy in multi-step organic synthesis. The compound’s physical characteristics, such as being a colorless liquid with a boiling point of 56-59°C at 56 mm Hg, also contribute to its ease of handling in many laboratory and industrial settings.

Applications in Organic Synthesis Beyond Pharmaceuticals

While its use in pharmaceutical synthesis, particularly concerning Cyp3A4 inhibition studies, is well-documented, the versatility of 1,1,2-Trimethoxyethane extends further. Its acetal nature makes it a candidate for reactions requiring the masking of aldehyde functionalities in the synthesis of fine chemicals, agrochemicals, or specialty materials. Researchers exploring novel synthetic routes for complex molecules may find this compound a valuable starting material or intermediate. Its consistent purity (≥99.0%) is critical for achieving predictable reaction outcomes.

Reliable Sourcing for Your Synthesis Needs

For chemists and procurement managers, securing a consistent supply of high-quality 1,1,2-Trimethoxyethane is essential. When you need to buy 1,1,2-Trimethoxyethane, partnering with a reputable manufacturer and supplier ensures you receive a product that meets specifications and arrives reliably. China is a significant hub for fine chemical manufacturing, offering competitive pricing for this compound. Always verify the CAS number (24332-20-5) and purity levels when making your purchase decisions. Exploring the price of 1,1,2-Trimethoxyethane from multiple trusted sources can help optimize your procurement budget.

At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing specialty chemicals that empower synthetic chemists. Our high-purity 1,1,2-Trimethoxyethane is manufactured to exacting standards. Contact us today to discuss your synthetic chemistry needs and to arrange for a quotation or sample of this valuable acetal.