In the intricate world of chemical synthesis, particularly within the pharmaceutical sector, the quality and reliability of reagents are paramount. 1,1,2-Trimethoxyethane, identified by its CAS number 24332-20-5, stands out as a crucial organic compound. Its molecular formula, C5H12O3, hints at its structure, and its synonyms like Methoxyacetaldehyde Dimethyl Acetal further clarify its chemical nature. This compound is not merely a chemical curiosity; it's a workhorse for researchers and manufacturers aiming for precision and efficacy in drug development.

The Significance of Purity and Properties

One of the most critical aspects of 1,1,2-Trimethoxyethane is its high purity, often specified at ≥99.0%. This level of purity is indispensable for applications where even trace impurities can significantly impact reaction outcomes or the final product's efficacy. Its physical properties, such as being a colorless to almost colorless liquid with a density of 0.932 g/mL at 25°C and a boiling point range of 56-59°C at 56 mm Hg, are also important considerations for process design and optimization. The flash point of 74°F classifies it as a flammable liquid, underscoring the need for careful handling and storage in cool, dry, and well-ventilated environments, away from incompatible substances.

Key Applications in Pharmaceutical Synthesis

The primary utility of 1,1,2-Trimethoxyethane, often referred to as Methoxyacetaldehyde Dimethyl Acetal, lies in its role as a reagent in sophisticated pharmaceutical research. It is specifically employed in the process of balancing oral exposure with Cyp3A4 inhibition, a critical factor when developing benzimidazole-based IGF-1R inhibitors. These inhibitors are part of ongoing research for therapeutic agents, particularly in oncology. The acetal functionality of 1,1,2-Trimethoxyethane allows it to act as a protective group for aldehydes during multi-step synthesis, a common and essential technique in building complex organic molecules required for modern pharmaceuticals.

Sourcing High-Quality 1,1,2-Trimethoxyethane

For procurement professionals and research scientists, finding a reliable manufacturer and supplier of 1,1,2-Trimethoxyethane in China is key. A reputable supplier ensures not only the chemical's quality and purity but also its consistent availability for both laboratory-scale research and larger production runs. When you buy 1,1,2-Trimethoxyethane, look for manufacturers that provide detailed specifications, including low moisture content (typically ≤0.25%) and minimal impurities (≤0.3%). Understanding the price of 1,1,2-Trimethoxyethane will also be a factor in your purchasing decision, so comparing offers from trusted sources is advisable.

As NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing high-quality fine chemicals like 1,1,2-Trimethoxyethane. We understand the demands of the pharmaceutical industry and strive to be your go-to supplier for essential research and manufacturing materials. Contact us to discuss your requirements for CAS 24332-20-5 and explore how our high-purity reagents can support your groundbreaking work.