The pharmaceutical industry constantly seeks high-quality raw materials to ensure the efficacy and safety of its products. For companies involved in the synthesis of Silodosin, a medication used to treat symptoms of benign prostatic hyperplasia (BPH), the intermediate 1-[3-(Benzyloxy)propyl]-5-formylindoline-7-carbonitrile is of paramount importance. This article delves into the significance of this chemical compound, its properties, and how pharmaceutical professionals can effectively source it from reliable suppliers.

The Significance of 1-[3-(Benzyloxy)propyl]-5-formylindoline-7-carbonitrile in Silodosin Production

Silodosin, a selective alpha-1 adrenergic receptor antagonist, works by relaxing the muscles in the prostate and bladder neck, thus alleviating urinary difficulties associated with BPH. The synthesis of Silodosin is a complex process that relies on specific precursor molecules to build its intricate structure. 1-[3-(Benzyloxy)propyl]-5-formylindoline-7-carbonitrile, often referred to by its CAS number 1375180-30-5, serves as a key intermediate in this synthesis. Its precise chemical structure ensures the correct stereochemistry and functional groups are present for subsequent reaction steps, ultimately leading to the high-purity Silodosin API.

Key Specifications for Procurement Managers

When procurement managers are tasked with sourcing 1-[3-(Benzyloxy)propyl]-5-formylindoline-7-carbonitrile, they need to focus on key specifications that guarantee quality. The product is typically supplied as a white powder, with a minimum assay requirement of ≥98.0%. Understanding its molecular formula (C20H20N2O2) and molecular weight (320.385) is essential for inventory management and process calculations. Working with a manufacturer that offers consistency in batch quality is vital for uninterrupted production lines. Many international buyers prefer to purchase this intermediate from established Chinese chemical companies due to competitive pricing and supply chain efficiency.

For R&D Scientists: Quality and Purity Matters

Research and development scientists require intermediates that are not only pure but also well-characterized. 1-[3-(Benzyloxy)propyl]-5-formylindoline-7-carbonitrile serves as a crucial starting point for process optimization and validation studies for Silodosin. Its consistent purity ensures reproducible results in laboratory settings, paving the way for successful scale-up. When seeking to buy this intermediate for R&D purposes, it's advisable to look for suppliers who can provide detailed technical data and certificates of analysis, confirming the compound's identity and purity.

Finding Reliable Suppliers and Manufacturers

The global market offers various suppliers for 1-[3-(Benzyloxy)propyl]-5-formylindoline-7-carbonitrile. However, identifying a reliable supplier or manufacturer is critical. Companies in China are often recognized for their manufacturing capabilities and competitive pricing. When making an inquiry, be sure to request a quote for your required quantities, whether for R&D or commercial use. A responsive supplier will provide prompt quotes and clear information about lead times and shipping. Building a strong relationship with a trusted supplier ensures a consistent and high-quality supply of this essential intermediate, supporting your pharmaceutical manufacturing goals.

In conclusion, 1-[3-(Benzyloxy)propyl]-5-formylindoline-7-carbonitrile is an indispensable component in the production of Silodosin. By understanding its specifications and partnering with reliable manufacturers and suppliers, pharmaceutical companies can ensure the quality and efficiency of their operations. If you are planning to purchase this intermediate, reach out to leading chemical providers to discuss your requirements and obtain a competitive price.