In the realm of pharmaceutical manufacturing, precise chemical intermediates are the bedrock of effective drug production. One such crucial compound is identified by its CAS number 1375180-30-5, chemically known as 1-[3-(Benzyloxy)propyl]-5-formylindoline-7-carbonitrile. This intermediate plays a pivotal role in the synthesis pathway of Silodosin, a widely prescribed medication for managing the symptoms of benign prostatic hyperplasia (BPH). For R&D scientists and procurement specialists, understanding the detailed specifications and procurement channels for this chemical is essential.

Chemical Profile of CAS 1375180-30-5

1-[3-(Benzyloxy)propyl]-5-formylindoline-7-carbonitrile, with the molecular formula C20H20N2O2 and a molecular weight of 320.385, is characterized by its appearance as a white powder. This physical state is typical for many high-purity organic intermediates used in pharmaceutical synthesis. The compound's structure is specifically designed to facilitate the subsequent chemical reactions required to form the Silodosin molecule. When you purchase this intermediate, ensuring it meets the specified assay of ≥98.0% is critical for maintaining the quality and yield of your Silodosin API.

Applications in Silodosin Synthesis and Beyond

The primary application for 1375180-30-5 is its use as a key building block in the synthesis of Silodosin. Silodosin, an alpha-blocker, helps to relax the muscles in the prostate and bladder neck, thereby improving urine flow and reducing urinary symptoms associated with an enlarged prostate. Beyond its direct role in Silodosin synthesis, this intermediate may also be of interest to researchers exploring similar molecular structures or developing novel pharmaceutical agents. The consistent availability of this compound from reliable manufacturers is vital for uninterrupted research and production cycles.

Procurement Strategies: Finding the Right Supplier

For companies looking to buy 1375180-30-5, identifying a trustworthy supplier is a strategic imperative. Factors to consider include the supplier's location (e.g., China, known for its robust chemical manufacturing sector), their commitment to quality control, their ability to provide timely quotes, and their capacity for handling both small and large orders. Negotiating the price for bulk quantities is a common practice for API manufacturers aiming to optimize their production costs. It is also beneficial to work with suppliers who offer detailed technical data sheets and support, which can be invaluable during process development and validation.

Ensuring Quality and Reliability in Supply

When evaluating potential suppliers, pay close attention to their quality management systems. A supplier that adheres to international standards and provides comprehensive documentation for their chemical intermediates like 1-[3-(Benzyloxy)propyl]-5-formylindoline-7-carbonitrile instills confidence. Whether your need is for research quantities or commercial volumes, securing a consistent and high-quality source is key. Many international buyers look to Chinese chemical companies for competitive pricing and diverse product portfolios. Ensuring that your chosen manufacturer has a strong emphasis on product purity and batch-to-batch consistency will directly benefit your Silodosin production line.

In summary, understanding the properties and applications of 1-[3-(Benzyloxy)propyl]-5-formylindoline-7-carbonitrile (CAS: 1375180-30-5) is crucial for stakeholders in the pharmaceutical industry. By prioritizing quality, reliability, and competitive pricing when sourcing this vital intermediate, companies can ensure the efficient and successful production of Silodosin. If you are seeking to purchase this compound, inquire with reputable chemical suppliers for accurate pricing and availability.