1,4-Difluorobenzene (CAS 540-36-3) is a foundational chemical intermediate that plays a significant role across various industrial and scientific sectors. Its unique fluorinated aromatic structure imparts valuable chemical and physical properties, making it a sought-after compound for synthesis and material development. For chemical professionals, understanding its characteristics, manufacturing processes, and applications is key to leveraging its potential effectively. As a premier 1,4-difluorobenzene manufacturer, we aim to provide comprehensive insights.

Key Properties and Chemical Profile

1,4-Difluorobenzene, with the molecular formula C6H4F2 and a molecular weight of approximately 114.09 g/mol, is typically a colorless to pale yellow transparent liquid. Its physical properties include a density of around 1.17 g/mL, a melting point of -13°C, and a boiling point of 88-89°C. The compound is characterized by its flash point of 36°F, indicating flammability, and a refractive index of 1.441. Purity specifications often demand an assay of ≥99.0%, with low moisture content (≤0.2%), ensuring its suitability for precise chemical reactions. These attributes are critical for researchers and formulators seeking consistent performance from their chemical raw materials.

Manufacturing and Quality Assurance

The production of high-purity 1,4-Difluorobenzene involves sophisticated synthesis techniques and stringent quality control measures. Manufacturers, especially those in China, employ advanced processes to achieve the desired assay levels and minimize impurities. Packaging is typically in 200 kg drums or customized containers, ensuring product integrity during transport and storage. Reliable suppliers provide comprehensive technical documentation, including COA and MSDS, to verify product quality and safety. For those looking to buy CAS 540-36-3, engaging with manufacturers who prioritize quality assurance is essential.

Diverse Applications in the Chemical Industry

The versatility of 1,4-Difluorobenzene makes it a critical intermediate across several industries:

  • Organic Synthesis: It serves as a fundamental building block for synthesizing a wide array of organic molecules. Its reactivity is leveraged in various coupling reactions and functional group transformations.
  • Pharmaceuticals: As a key intermediate, it is used in the production of active pharmaceutical ingredients (APIs) and drug candidates, where the fluorine atoms contribute to improved pharmacokinetic properties and therapeutic efficacy. Professionals often inquire about the 1,4-difluorobenzene price for pharma to secure supply for drug development pipelines.
  • Agrochemicals: It is instrumental in the synthesis of advanced pesticides, herbicides, and fungicides, enhancing their efficacy and targeted action in crop protection.
  • Liquid Crystals and Materials Science: Its unique electronic properties make it valuable for developing liquid crystals used in display technologies and other advanced functional materials that require specific optical or electronic characteristics.

Sourcing and Partnership Opportunities

When sourcing 1,4-Difluorobenzene, chemical professionals should seek out established suppliers known for their reliability, product quality, and competitive pricing. China has become a significant hub for chemical manufacturing, offering many reliable p-difluorobenzene suppliers. NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier committed to excellence in providing high-purity intermediates. We welcome consultations for bulk purchases and custom synthesis needs, ensuring you receive the quality and service required for your projects. Contact us to inquire about obtaining 1,4-Difluorobenzene and to discuss your specific requirements.