1,6-Dibromohexane: An Essential Molecule for Advanced Chemical Synthesis
In the realm of fine chemicals and organic synthesis, certain molecules stand out for their versatility and indispensable role in creating advanced materials and pharmaceuticals. 1,6-Dibromohexane (CAS: 629-03-8) is one such compound, prized for its dual functionality and utility as a robust building block. Understanding its characteristics and applications is essential for researchers and industrial buyers alike.
Chemical Identity and Properties
1,6-Dibromohexane, also known as hexamethylene dibromide, is an aliphatic dibromoalkane with the molecular formula C6H12Br2. Its structure features a six-carbon chain with bromine atoms situated at each terminus. This arrangement provides two reactive sites, making it an effective alkylating agent and a valuable intermediate in many synthetic routes. Typically presented as a colorless to pale yellow liquid, it possesses a density of approximately 1.586 g/mL and a relatively high boiling point of 243°C, indicating good thermal stability under controlled conditions.
Synthesis and Purity Standards
The production of 1,6-Dibromohexane commonly involves the bromination of 1,6-hexanediol, a straightforward reaction yielding the desired dibrominated product. The critical factor for its use in sophisticated applications is purity. Manufacturers strive to achieve assay levels of 99.0% or higher, as confirmed by Gas Chromatography (GC). This high purity is paramount, especially when the compound is used in pharmaceutical synthesis or the development of performance polymers, where even minor impurities can compromise the final product's efficacy and integrity.
Diverse Applications Across Industries
The reactivity and structural attributes of 1,6-Dibromohexane lend themselves to a broad spectrum of applications:
- Organic Synthesis: It serves as a fundamental intermediate for constructing complex organic molecules. Its C6 chain acts as a flexible spacer, crucial in creating specific molecular architectures.
- Pharmaceutical Industry: It plays a role in the synthesis of certain active pharmaceutical ingredients (APIs) and intermediates for drug development. Its historical use in hypotensive agents and ongoing research into new therapeutic compounds highlight its importance.
- Polymer Science: As a cross-linking agent, it enhances the properties of polymers. It's also used as a monomer in creating specialty polymers, such as conductive polyfluorene ionomers for advanced energy applications like fuel cells.
- Materials Science Research: Researchers utilize it for creating molecular bridges, sensors, and other functional materials where precise spatial arrangements of reactive groups are needed.
Procurement Advice for B2B Buyers
For businesses looking to buy 1,6-Dibromohexane, partnering with a reputable manufacturer is essential. Key considerations include sourcing from suppliers who guarantee high purity (≥99.0%), offer consistent quality across batches, provide comprehensive technical documentation (like CoAs), and maintain a reliable supply chain. Competitive pricing, particularly for bulk purchases, and responsive customer service are also important factors when selecting a supplier, especially from international markets like China.
By understanding the critical properties and applications of 1,6-Dibromohexane, and by choosing a trusted supplier, industries can effectively leverage this essential molecule to drive innovation and product development.
Perspectives & Insights
Core Pioneer 24
“Understanding its characteristics and applications is essential for researchers and industrial buyers alike.”
Silicon Explorer X
“Chemical Identity and Properties 1,6-Dibromohexane, also known as hexamethylene dibromide, is an aliphatic dibromoalkane with the molecular formula C6H12Br2.”
Quantum Catalyst AI
“Its structure features a six-carbon chain with bromine atoms situated at each terminus.”