1-Bromo-3-methoxypropane: Essential Intermediate for Brinzolamide and Beyond
The chemical industry relies on a vast array of intermediates to facilitate the synthesis of complex compounds. Among these, 1-Bromo-3-methoxypropane (CAS 36865-41-5), also referred to as 3-Bromopropyl Methyl Ether, holds a significant position, particularly within the pharmaceutical sector. Its specific chemical structure and reactivity make it an indispensable component for creating advanced molecular entities.
The Chemical Profile of 1-Bromo-3-methoxypropane
This chemical is typically found as a colorless to light yellow liquid, with a purity level usually guaranteed at 98.0% or higher. Its molecular formula, C4H9BrO, indicates a relatively simple yet highly functional structure. The key feature is the terminal bromine atom on the propyl chain, which acts as an effective leaving group. This characteristic renders 1-Bromo-3-methoxypropane a potent alkylating agent, capable of reacting with nucleophiles to form new covalent bonds. Such reactivity is fundamental in building the intricate structures required for modern pharmaceuticals and fine chemicals.
Pivotal Role in Pharmaceutical Synthesis: Brinzolamide
The most prominent application of 1-Bromo-3-methoxypropane is its role as a crucial intermediate in the synthesis of Brinzolamide. Brinzolamide is a widely recognized active pharmaceutical ingredient (API) used in the treatment of ocular hypertension and open-angle glaucoma. The synthetic pathways leading to Brinzolamide typically involve the precise introduction of specific functional groups, and 1-Bromo-3-methoxypropane is essential for attaching the 3-methoxypropyl moiety. For pharmaceutical companies and contract manufacturers looking to source Brinzolamide intermediates, ensuring the purity and consistent quality of this key precursor is vital. A reliable supplier offering high-assay 1-Bromo-3-methoxypropane is essential for efficient and cost-effective API production. When you need to buy this intermediate, looking for manufacturers experienced in pharmaceutical building blocks is recommended.
Versatility in General Organic Synthesis
Beyond its specific pharmaceutical application, 1-Bromo-3-methoxypropane serves as a versatile building block in general organic synthesis. Its ability to participate in alkylation reactions makes it useful for a range of transformations, including the formation of ethers and amines. This versatility allows chemists to incorporate specific structural features into target molecules, aiding in the development of new materials and complex organic compounds. Its reliable reactivity and manageable physical properties make it a valuable tool for chemists in research and industrial settings.
Strategic Sourcing and Supply
For businesses in need of 1-Bromo-3-methoxypropane, strategic sourcing is key. Partnering with reputable manufacturers and suppliers, particularly those based in China known for their chemical production capabilities, can ensure access to high-quality material at competitive prices. It is important to work with suppliers who can provide detailed product specifications, Certificates of Analysis (CoA), and reliable delivery schedules. If you are looking to purchase 1-Bromo-3-methoxypropane, consider engaging with experienced chemical manufacturers who understand the stringent requirements of the pharmaceutical industry. We are a leading manufacturer and supplier committed to providing excellent quality intermediates to support your innovations.
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Perspectives & Insights
Future Origin 2025
“If you are looking to purchase 1-Bromo-3-methoxypropane, consider engaging with experienced chemical manufacturers who understand the stringent requirements of the pharmaceutical industry.”
Core Analyst 01
“We are a leading manufacturer and supplier committed to providing excellent quality intermediates to support your innovations.”
Silicon Seeker One
“Keywords for Supply: 1-bromo-3-methoxypropane, pharmaceutical intermediate, Brinzolamide synthesis, organic chemistry, alkylation, chemical supplier, buy intermediate, fine chemicals.”