For professionals in the chemical and pharmaceutical industries, a thorough understanding of key chemical intermediates is crucial for successful research, development, and production. 1-Bromo-3-methoxypropane, identified by CAS number 36865-41-5 and also known as 3-Bromopropyl Methyl Ether, is a compound that warrants close attention due to its significant utility.

Physical and Chemical Characteristics

1-Bromo-3-methoxypropane typically presents as a colorless to light yellow liquid. Its chemical formula is C4H9BrO, giving it a molecular weight of approximately 153.02 g/mol. The molecule is characterized by a methyl ether group attached to a propyl chain, with a bromine atom at the terminal position of the propyl chain. This bromine atom is the focal point of its reactivity, serving as an excellent leaving group in nucleophilic substitution and alkylation reactions. Its purity level, often specified as ≥98.0% via Gas Chromatography (GC), is a critical parameter for its intended applications, particularly in pharmaceutical synthesis where precise stoichiometry and minimal impurities are essential.

Applications in Pharmaceutical and Organic Synthesis

The primary application that highlights the importance of 1-Bromo-3-methoxypropane is its role as a key intermediate in the manufacturing process of Brinzolamide. Brinzolamide is a widely used ophthalmic drug for managing glaucoma and ocular hypertension. The specific structure of 1-Bromo-3-methoxypropane allows for its efficient incorporation into the complex molecular architecture of Brinzolamide. Its ability to act as an alkylating agent means it can introduce the 3-methoxypropyl group onto various substrates, a common strategy in building complex organic molecules. For procurement managers looking to buy pharmaceutical intermediates, sourcing this compound from a reputable manufacturer ensures the high purity and consistent quality required for successful drug synthesis.

Furthermore, 1-Bromo-3-methoxypropane finds utility in broader organic synthesis contexts. Chemists utilize it as a building block for creating a diverse array of organic compounds, including specialty chemicals and research materials. Its reactivity allows for the formation of new carbon-carbon or carbon-heteroatom bonds, which are fundamental transformations in synthetic organic chemistry.

Selecting a Reliable Supplier

When sourcing 1-Bromo-3-methoxypropane, it is imperative to partner with a reliable chemical supplier. Key considerations include the supplier's ability to provide detailed product specifications, a Certificate of Analysis (CoA) confirming purity and identity, and responsive customer service. Manufacturers who can offer flexible packaging options and maintain a stable supply chain are particularly valuable. For companies requiring this intermediate, seeking out established chemical manufacturers and suppliers in China can provide access to competitive pricing and substantial production capacities. We are a trusted manufacturer and supplier, committed to providing high-quality 1-Bromo-3-methoxypropane to meet your diverse chemical needs.

Keywords for Understanding: 1-bromo-3-methoxypropane, chemical properties, organic synthesis, pharmaceutical intermediate, Brinzolamide, alkylating agent, supplier, manufacturer, CAS 36865-41-5.