In the complex landscape of chemical synthesis, the selection of the right intermediates is paramount for achieving desired outcomes in research and manufacturing. 1-Chloro-2-iodobenzene (CAS 615-41-8) is a highly valuable organic compound known for its utility as a synthetic intermediate. This article provides an overview of its key properties, diverse applications, and essential tips for procurement managers and research scientists looking to buy 1-chloro-2-iodobenzene.

Key Properties of 1-Chloro-2-iodobenzene

1-Chloro-2-iodobenzene, with the molecular formula C6H4ClI, is an aromatic organic compound that plays a significant role in various chemical reactions. Understanding its physical and chemical properties is crucial for its effective application:

  • Appearance: Typically observed as a light yellow liquid.
  • Purity: High purity levels, usually ≥99%, are standard for most demanding applications, ensuring reliable and predictable reaction results.
  • Boiling Point: Its boiling point of 234-235°C indicates good thermal stability under common laboratory and industrial processing conditions.
  • Density: The density is approximately 1.952 g/mL at 25°C, a useful parameter for material handling and calculations.
  • CAS Number: 615-41-8 is the internationally recognized identifier for this chemical.

When sourcing this chemical, always refer to the Certificate of Analysis (CoA) provided by the supplier to confirm its specifications.

Diverse Applications of 1-Chloro-2-iodobenzene

The versatile nature of 1-Chloro-2-iodobenzene stems from the presence of two different halogen atoms on the benzene ring, each offering distinct reactivity. This makes it a prized intermediate in:

  • Organic Synthesis: It serves as a fundamental building block for creating more complex organic molecules. Its participation in various coupling reactions, such as Suzuki, Sonogashira, and Heck couplings, is vital for forming carbon-carbon bonds. This capability is essential for synthesizing advanced materials, agrochemicals, and specialty chemicals.
  • Pharmaceutical Intermediates: The pharmaceutical industry extensively uses 1-Chloro-2-iodobenzene in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates. Its structure allows for precise functionalization and the construction of complex molecular architectures required for therapeutic efficacy. Researchers often search for 1-chloro-2-iodobenzene for sale to support their drug discovery efforts.
  • Chemical Research: Academic and industrial research laboratories utilize this compound to explore new synthetic methodologies, develop novel catalysts, and investigate reaction mechanisms.

The availability of this intermediate from a reliable manufacturer greatly facilitates innovative research.

Tips for Sourcing 1-Chloro-2-iodobenzene

Procuring chemicals requires careful consideration to ensure quality, reliability, and cost-effectiveness. Here are some tips for buyers:

  • Verify Purity: Always confirm the minimum assay of the product. For critical applications, ≥99% purity is generally recommended.
  • Choose Reputable Suppliers: Partner with established manufacturers and suppliers known for their quality control and customer service. Companies based in China, like us, often provide competitive pricing and a broad product portfolio.
  • Request Samples: Before placing a large order, requesting a sample allows you to test the product's quality and suitability for your specific application.
  • Check Documentation: Ensure that suppliers can provide essential documents such as the Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and relevant regulatory compliance information.
  • Consider Bulk Pricing: If you require larger quantities, inquire about bulk discounts or contract pricing to optimize your procurement costs. Investigating the best 1-chloro-2-iodobenzene price is part of smart procurement.

As a leading 1-chloro-2-iodobenzene supplier based in China, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality chemical intermediates with exceptional service. We strive to be your trusted partner for all your chemical sourcing needs. Contact us today to learn more about our product offerings and to request a quote.