In the dynamic world of chemical manufacturing and research, understanding the properties and applications of key intermediates is crucial for success. 1-Piperazinecarbaldehyde, identified by its CAS number 7755-92-2, is a compound that has gained significant attention for its utility in various synthesis processes. This article delves into its characteristics, applications, and provides guidance on sourcing this important material, particularly from manufacturers in China.

Understanding the Properties of 1-Piperazinecarbaldehyde:

1-Piperazinecarbaldehyde is characterized by its chemical formula C5H10N2O and a molecular weight of approximately 114.15 g/mol. The compound typically presents as a white crystalline powder with a stated purity of 95%+. Its melting point ranges between 88-91 °C, and it has a boiling point of 264-266 °C at atmospheric pressure. The density is recorded as 1.107 g/mL at 25 °C. Stability is generally good under normal storage conditions, recommending storage at 2-8 °C. The refractive index is noted as n20/D 1.512, and its flash point is 215 °F.

For procurement managers and chemists looking to buy 1-Piperazinecarbaldehyde, these specifications are vital for evaluating its suitability for specific applications. The presence of detailed product information, such as an acidity factor (pKa) of 8.58±0.10 (predicted), further aids in understanding its chemical behavior.

Diverse Applications in Chemical Synthesis:

The primary application of 1-Piperazinecarbaldehyde lies in its role as an intermediate in organic synthesis. Its structure, containing both a reactive aldehyde group and a secondary amine within the piperazine ring, allows for a broad spectrum of chemical modifications. This makes it a valuable building block for:

  • Pharmaceutical Synthesis: As a key intermediate in the production of Active Pharmaceutical Ingredients (APIs) and drug candidates.
  • Fine Chemical Manufacturing: Used in the creation of specialty chemicals requiring specific heterocyclic structures.
  • Research and Development: An essential reagent for exploring new synthetic pathways and developing novel chemical entities.

When searching for a supplier, consider manufacturers that can provide consistent quality and reliable supply chains. For those looking to purchase CAS 7755-92-2, identifying suppliers with extensive experience in handling such intermediates is recommended.

Sourcing Strategies for 1-Piperazinecarbaldehyde:

China has emerged as a significant hub for chemical manufacturing, offering competitive pricing and a vast array of intermediates. When sourcing 1-Piperazinecarbaldehyde from Chinese manufacturers, it's important to conduct thorough due diligence. Look for suppliers with established export procedures, good communication channels, and a commitment to international quality standards.

Procurement managers should request detailed quotations and compare offerings from various manufacturers. Consider the minimum order quantity (MOQ) and packaging options that best suit your production scale. Many reputable manufacturers will provide sample quantities for testing, allowing you to verify the quality before making a bulk purchase. Working directly with a manufacturer ensures better control over the supply chain and potentially more favorable pricing for this critical organic synthesis reagent.

In conclusion, 1-Piperazinecarbaldehyde (CAS: 7755-92-2) is a versatile and important intermediate. By understanding its properties and applications, and by employing effective sourcing strategies with reputable manufacturers, organizations can secure a high-quality supply to drive their chemical synthesis endeavors forward.