The chemical industry constantly seeks versatile and reliable building blocks to drive innovation in drug discovery and the development of advanced materials. 1-Piperazinecarbaldehyde (CAS: 7755-92-2) has emerged as a compound of significant interest due to its unique structural features and broad applicability, especially within the pharmaceutical and fine chemical sectors.

Chemical Profile and Reactivity:

1-Piperazinecarbaldehyde is characterized by its molecular formula C5H10N2O and a molecular weight of approximately 114.15 g/mol. Typically supplied as a white crystalline powder with a purity of 95% or higher, it possesses a melting point of 88-91°C. The compound's structure combines a piperazine ring with a formyl substituent, endowing it with valuable reactivity. The amine functionality within the piperazine ring can undergo various reactions such as alkylation, acylation, and salt formation. Simultaneously, the aldehyde group on the nitrogen atom is susceptible to nucleophilic attack, oxidation, and reduction, making it a versatile intermediate for synthetic chemists.

For R&D scientists and procurement managers, understanding these properties is key to effectively utilizing 1-Piperazinecarbaldehyde in synthesis. When looking to buy 1-Piperazinecarbaldehyde, prioritizing suppliers who provide comprehensive technical data, including stability and storage recommendations (e.g., 2-8°C), ensures optimal use of the material.

Applications in Pharmaceutical and Fine Chemicals:

The pharmaceutical industry extensively utilizes 1-Piperazinecarbaldehyde as a crucial intermediate in the synthesis of various Active Pharmaceutical Ingredients (APIs) and drug candidates. Its incorporation into molecular structures can impart desirable pharmacokinetic properties or serve as a core scaffold for targeted therapies. Researchers leverage this compound to build complex heterocyclic systems that are common in many modern medicines.

Beyond pharmaceuticals, 1-Piperazinecarbaldehyde finds applications in the broader fine chemical sector, including the synthesis of:

  • Specialty reagents
  • Agrochemical intermediates
  • Materials for electronic applications
  • Research chemicals for scientific exploration

The demand for high-purity 1-Piperazinecarbaldehyde necessitates sourcing from reliable manufacturers. Many companies choose to purchase CAS 7755-92-2 from specialized chemical suppliers, including those in China, known for their competitive pricing and broad product portfolios.

Sourcing and Procurement Considerations:

When procuring 1-Piperazinecarbaldehyde, several factors are crucial for procurement professionals. Identifying manufacturers that adhere to strict quality control measures is essential. Requesting Certificates of Analysis (CoAs) for each batch ensures that the material meets the specified purity and quality standards. Furthermore, establishing a stable supply chain through partnerships with reputable suppliers, who can offer consistent availability and timely delivery, is vital for uninterrupted production or research timelines.

Exploring various suppliers for CAS 7755-92-2 will allow procurement managers to compare pricing, lead times, and service offerings. Engaging directly with manufacturers, particularly those with a strong export presence, can often provide the best value and a more transparent procurement process. Always inquire about sample availability to validate product quality before making bulk purchase decisions.

In summary, 1-Piperazinecarbaldehyde (CAS: 7755-92-2) is a valuable and versatile building block that plays a critical role in the pharmaceutical and fine chemical industries. By focusing on quality, reliability, and strategic sourcing, organizations can effectively leverage this compound to advance their synthetic chemistry endeavors.