The field of steroid synthesis is complex and relies heavily on precise chemical intermediates to achieve desired therapeutic compounds. 11α-Hydroxyprogesterone, identified by CAS 80-75-1, is a critical compound in this domain, serving as a cornerstone for various synthetic pathways. For researchers and pharmaceutical manufacturers, understanding its properties and sourcing it effectively is paramount. This article highlights its importance and guides on how to procure it from reliable sources.

The Chemical Significance of 11α-Hydroxyprogesterone

11α-Hydroxyprogesterone is a progesterone derivative characterized by the presence of a hydroxyl group at the 11-alpha position. This structural modification is key to its utility. Its molecular formula is C21H30O3, with a molecular weight of 330.46 g/mol. It is typically supplied as a fine crystalline powder, usually white to light beige, with a high purity level of 99%. This high purity ensures that it performs reliably in sensitive synthesis reactions, minimizing unwanted byproducts and maximizing the yield of the desired steroid compounds.

Applications in Steroid Synthesis and Beyond

  • Synthesis of Corticosteroids: It is a vital precursor in the multi-step synthesis of corticosteroids, a class of drugs used to treat inflammation and various other conditions.
  • Research in Endocrinology: Its role as a modified steroid hormone makes it valuable for studying hormonal regulation, metabolic pathways, and the effects of hormone analogs. Researchers frequently buy 11α-Hydroxyprogesterone for these specific investigations.
  • Development of Novel Steroids: The hydroxyl group at the 11-alpha position offers a reactive site for further chemical modifications, enabling the creation of novel steroid compounds with potentially enhanced or altered therapeutic properties.

Sourcing 11α-Hydroxyprogesterone: A Focus on Manufacturers

For professionals seeking to purchase 11α-Hydroxyprogesterone (CAS 80-75-1), partnering with reputable manufacturers is the most effective strategy. Key considerations when selecting a supplier include:

  • Quality Assurance: Prioritize suppliers who provide detailed Certificates of Analysis (CoA) that confirm the 99% purity and other specifications.
  • Manufacturing Expertise: Look for manufacturers with established processes for producing steroid intermediates and a strong understanding of the pharmaceutical industry's requirements.
  • Global Supply Chain: Companies with experience in international export, particularly from regions like China known for chemical manufacturing, can ensure reliable and timely delivery.
  • Competitive Pricing: Direct engagement with manufacturers often leads to better pricing, especially for bulk orders, allowing for cost-effective research and production.

As a dedicated manufacturer and supplier of high-quality pharmaceutical intermediates, we are well-positioned to meet your needs for 11α-Hydroxyprogesterone. We invite you to contact us for detailed product information, pricing quotes, and to discuss how we can be your trusted partner in steroid synthesis. Ensuring a stable supply of this critical intermediate is key to advancing your research and production goals.

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