In the realm of chemical synthesis, identifying versatile and reliable intermediates is fundamental for researchers and manufacturers alike. 2'-Bromo-4-biphenylcarbonitrile, identified by its CAS number 482377-55-9, stands out as a key chemical intermediate due to its unique structural characteristics and broad applicability. This article aims to provide essential information for procurement managers and chemists regarding its properties, applications, and how to source it effectively.

Understanding the Chemistry: 2'-Bromo-4-biphenylcarbonitrile

2'-Bromo-4-biphenylcarbonitrile (MF: C13H8BrN) is a derivative of biphenyl, featuring a bromine atom and a nitrile group. Its molecular weight is 258.113 g/mol. Typically presented as an off-white solid powder, it possesses a melting point in the range of 88-89 °C, as indicated in some literature, and a boiling point of 366.4 ± 25.0 °C at 760 mmHg. Its density is approximately 1.5 ± 0.1 g/cm³. A critical specification for this compound is its purity, which is commonly supplied at a minimum of 98%, ensuring its effectiveness in demanding synthetic processes.

Key Applications and Uses

The utility of 2'-Bromo-4-biphenylcarbonitrile as a chemical intermediate spans several critical industries. Its primary applications include:

  • Pharmaceutical Synthesis: It serves as a vital building block for the synthesis of active pharmaceutical ingredients (APIs) and complex drug molecules. The bromine atom allows for facile coupling reactions, while the nitrile group offers pathways to other functional groups.
  • Fine Chemical Production: This compound is utilized in the broader fine chemical industry for creating specialized molecules with targeted properties for various industrial applications.
  • Materials Science: Researchers in materials science may employ 2'-Bromo-4-biphenylcarbonitrile in the development of organic electronics, such as OLEDs, due to the electronic properties inherent in its biphenyl structure.

Sourcing Strategies for Buyers

For professionals looking to buy 2'-Bromo-4-biphenylcarbonitrile, identifying a trustworthy supplier is paramount. China is a major hub for chemical manufacturing, offering access to competitive pricing and a wide range of products. When seeking a manufacturer or supplier, consider the following:

  • Purity and Quality Control: Always verify the minimum purity (98%) and request a Certificate of Analysis (CoA) to ensure product quality.
  • Supplier Reliability: Look for suppliers with a proven track record, positive customer reviews, and a commitment to consistent supply.
  • Pricing and Volume: Obtain quotes for different quantities to find the most cost-effective solution for your needs. Requesting free samples is often a good starting point for evaluating a supplier.
  • Technical Support: Choose suppliers who can offer technical assistance or product information to aid in your synthesis planning.

Conclusion

2'-Bromo-4-biphenylcarbonitrile is an indispensable intermediate for many chemical synthesis endeavors, particularly in the pharmaceutical sector. By understanding its properties and adopting strategic sourcing practices, buyers can ensure they obtain a high-quality, reliably supplied product. We pride ourselves on being a leading manufacturer and supplier of such critical chemical intermediates from China. Contact us today to get a quote or a free sample of 2'-Bromo-4-biphenylcarbonitrile and discuss how we can meet your procurement needs efficiently and cost-effectively.