The intricate world of pharmaceutical synthesis relies heavily on specialized chemical intermediates that act as foundational building blocks. Among these vital compounds is 2'-Bromo-4-biphenylcarbonitrile (CAS: 482377-55-9), a molecule prized for its unique structural features and reactivity. For Research and Development (R&D) scientists and product formulators, understanding the capabilities and sourcing of this intermediate is crucial for driving innovation and achieving synthesis goals.

What is 2'-Bromo-4-biphenylcarbonitrile?

2'-Bromo-4-biphenylcarbonitrile, with its molecular formula C13H8BrN, is a derivative of biphenyl. It is characterized by the presence of a bromine atom at the 2' position and a nitrile group at the 4 position of the biphenyl structure. Typically supplied as an off-white solid powder with a minimum purity of 98%, this compound offers a stable and reliable platform for chemical transformations.

Significance in Pharmaceutical Synthesis

The chemical structure of 2'-Bromo-4-biphenylcarbonitrile makes it an exceptionally versatile intermediate in the synthesis of pharmaceuticals. The bromine atom can readily participate in cross-coupling reactions, such as Suzuki, Heck, or Sonogashira couplings, allowing for the introduction of diverse functional groups and the construction of complex molecular scaffolds. The nitrile group can also be transformed into various other functional groups, including amines, carboxylic acids, or amides, further expanding its utility.

R&D scientists often select this intermediate for its ability to form key structural motifs found in many biologically active molecules. Its biphenyl core provides a rigid framework, which can be essential for receptor binding and pharmacokinetic properties of drug candidates. By incorporating 2'-Bromo-4-biphenylcarbonitrile into synthetic routes, pharmaceutical companies can efficiently develop novel therapeutics for a wide range of medical conditions.

Advantages for Formulators and Buyers

For product formulators and procurement managers, sourcing 2'-Bromo-4-biphenylcarbonitrile from a reliable manufacturer in China offers distinct advantages. These include competitive pricing, consistent quality assurance (ensuring the 98% minimum purity), and the ability to secure a stable supply chain. When you buy this intermediate, you are investing in a proven component that can streamline your synthesis process, reduce the risk of batch failures, and ultimately accelerate your product development timeline.

Exploring Applications and Beyond

While its primary application is in pharmaceutical synthesis, 2'-Bromo-4-biphenylcarbonitrile also finds use in the development of fine chemicals and advanced materials, such as organic semiconductors and components for OLEDs. Its biphenyl structure is a common feature in materials science, contributing to optical and electronic properties.

If your research or manufacturing process requires a dependable source of 2'-Bromo-4-biphenylcarbonitrile, consider partnering with expert chemical suppliers. We are dedicated to providing high-quality intermediates to support your critical R&D and production needs. Contact us today to discuss your requirements, request a sample, and secure a competitive quote for this essential chemical building block.