In the realm of fine chemicals, certain compounds serve as indispensable building blocks for more complex and valuable molecules. 2-Chloro-1,4-Naphthoquinone (CAS 1010-60-2) is one such compound, prized for its specific chemical properties and its crucial role as a pharmaceutical intermediate. Understanding these characteristics is vital for R&D scientists and production managers seeking to leverage its potential in synthesis and manufacturing.

Chemical and Physical Profile of 2-Chloro-1,4-Naphthoquinone

2-Chloro-1,4-Naphthoquinone, with the molecular formula C10H5ClO2 and a molecular weight of approximately 192.6 g/mol, presents as a yellow crystalline solid. Its defined physical attributes, such as a melting point typically between 108-109°C and a predicted boiling point of 308.0±42.0 °C, indicate its stability under standard processing conditions. Its density is noted around 1.42 g/cm³, and it exhibits slight solubility in chloroform. A flash point of 129.3°C suggests moderate flammability. Critically for storage and handling, it is described as moisture-sensitive, necessitating sealed, dry storage conditions, ideally between 2-8°C, to maintain its integrity and purity.

These properties are not merely descriptive; they dictate how the compound can be effectively used in various chemical reactions. For manufacturers and buyers, these specifications are essential for ensuring the material is fit for purpose and that appropriate handling and storage protocols are implemented. As a product from a trusted manufacturer, such as NINGBO INNO PHARMCHEM CO.,LTD., these details are meticulously controlled and communicated.

The Pivotal Role in Atovaquone Synthesis

The primary industrial application of 2-Chloro-1,4-Naphthoquinone lies in its function as a key intermediate in the synthesis of Atovaquone. Atovaquone is a vital medication used to treat serious infections, including malaria and Pneumocystis pneumonia (PCP). The chemical structure of 2-Chloro-1,4-Naphthoquinone provides the necessary chloronaphthoquinone framework that is elaborated upon during the synthesis of Atovaquone. This makes it an indispensable component in the pharmaceutical supply chain for these critical treatments.

Sourcing Considerations and Manufacturer Reliability

For organizations aiming to purchase 2-Chloro-1,4-Naphthoquinone, selecting a reliable supplier is as important as understanding the product's properties. A reputable 2-Chloro-1,4-Naphthoquinone manufacturer in China, like NINGBO INNO PHARMCHEM CO.,LTD., will offer consistent quality, adherence to strict specifications (e.g., purity, impurity profiles), and dependable logistics. When considering the price, it's crucial to evaluate the total value proposition, which includes not just the cost per kilogram but also the assurance of product quality and supply chain reliability. Whether for R&D or large-scale production, partnering with an experienced fine chemical supplier ensures that critical pharmaceutical synthesis can proceed without interruption.

In essence, 2-Chloro-1,4-Naphthoquinone is more than just a chemical compound; it is a vital link in the chain of producing advanced pharmaceuticals. Its specific chemical characteristics, coupled with the reliability of its suppliers, underscore its importance in the global fine chemical market.