2-Fluoro-6-methylbenzoic Acid: Chemical Properties and Pharmaceutical Applications
In the realm of specialty chemicals, compounds that offer unique structural attributes and versatile reactivity are highly valued, particularly for pharmaceutical applications. 2-Fluoro-6-methylbenzoic Acid (CAS:90259-27-1) is a prime example, recognized for its utility as a key intermediate in the synthesis of advanced APIs. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a manufacturer and supplier of this important chemical.
Chemically, 2-Fluoro-6-methylbenzoic Acid is an ortho-substituted benzoic acid derivative. Its molecular formula is C8H7FO2, with a molecular weight of 154.14 g/mol. It typically presents as a white powder, with a melting point in the range of 124-128°C. The presence of the fluorine atom and the methyl group at adjacent positions to the carboxylic acid group dictates its reactivity and makes it a valuable building block in targeted organic synthesis.
The pharmaceutical industry leverages the distinct chemical properties of 2-Fluoro-6-methylbenzoic Acid for several critical applications. Notably, it serves as a precursor in the synthesis of various targeted therapies. For instance, it has been utilized in the development of epidermal growth factor receptor (EGFR) inhibitors, a class of drugs vital in modern oncology. The specific placement of substituents on the aromatic ring allows for controlled functionalization, leading to the creation of molecules with desired biological activity.
Furthermore, this compound is recognized for its role in the production of avacopan, a therapeutic agent designed to treat ANCA-associated vasculitis. The synthesis of such complex and impactful drugs necessitates reliable access to high-quality intermediates. For procurement managers and researchers, identifying a dependable supplier who can consistently provide 2-Fluoro-6-methylbenzoic Acid with the required purity (often >97%) is paramount.
As a leading manufacturer and supplier from China, we are committed to delivering excellence. Our production facilities are equipped to ensure that 2-Fluoro-6-methylbenzoic Acid meets stringent quality standards. We understand the importance of consistent supply and competitive pricing for our clients in the pharmaceutical and chemical research sectors. Whether you need this intermediate for early-stage drug discovery or for large-scale manufacturing, we are prepared to meet your demands.
For organizations looking to purchase 2-Fluoro-6-methylbenzoic Acid, understanding its chemical properties and application scope is key. We encourage you to contact us to learn more about our product specifications, pricing, and to initiate an inquiry for purchase. Our aim is to be your trusted partner, providing the essential chemical building blocks that drive pharmaceutical innovation and success.
Perspectives & Insights
Future Origin 2025
“It typically presents as a white powder, with a melting point in the range of 124-128°C.”
Core Analyst 01
“The presence of the fluorine atom and the methyl group at adjacent positions to the carboxylic acid group dictates its reactivity and makes it a valuable building block in targeted organic synthesis.”
Silicon Seeker One
“The pharmaceutical industry leverages the distinct chemical properties of 2-Fluoro-6-methylbenzoic Acid for several critical applications.”