In the dynamic field of pharmaceutical research and development, sourcing high-quality chemical intermediates is paramount. Among these, 2-Fluoro-6-methylbenzoic Acid (CAS:90259-27-1) stands out as a crucial building block. As a manufacturer specializing in fine chemical intermediates, we understand the demands of the pharmaceutical industry and are committed to providing reliable access to this essential compound.

2-Fluoro-6-methylbenzoic Acid, a fluorinated benzoic acid derivative, plays a pivotal role in the synthesis of various Active Pharmaceutical Ingredients (APIs). Its unique molecular structure, featuring both a fluorine atom and a methyl group ortho to the carboxylic acid, allows for specific and efficient chemical reactions. This makes it an indispensable tool for medicinal chemists aiming to develop novel therapeutic agents.

One significant application highlighted in recent literature is its use in the synthesis of epidermal growth factor receptor (EGFR) inhibitors. In these synthesis pathways, the methyl group can undergo radical bromination, paving the way for nucleophilic substitution reactions. Subsequently, the carboxylic acid functionality is utilized for coupling with other molecular motifs, a common strategy in creating potent drug candidates. The precise nature of these reactions underscores the importance of sourcing intermediates with high purity and consistent quality.

Furthermore, 2-Fluoro-6-methylbenzoic Acid is recognized as a key building block in the production of avacopan. Avacopan is a significant therapeutic agent used in the treatment of anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis, an autoimmune disease. The integration of this intermediate into the synthesis of avacopan demonstrates its value in creating life-changing medications. For procurement managers and research scientists seeking to buy this crucial component, understanding its applications is key to ensuring successful project outcomes.

As a dedicated manufacturer and supplier, we pride ourselves on offering 2-Fluoro-6-methylbenzoic Acid with a purity of over 97%. This high level of purity is essential for pharmaceutical applications, minimizing side reactions and ensuring the integrity of the final API. We cater to a global clientele, providing efficient supply chain solutions and competitive pricing for both research quantities and bulk orders. If you are looking to purchase this vital intermediate, consider us your trusted partner.

For companies involved in drug discovery, medicinal chemistry, or the large-scale manufacturing of APIs, securing a stable and high-quality supply of 2-Fluoro-6-methylbenzoic Acid is a strategic imperative. We are equipped to meet these demands, offering not just products but also the assurance of reliability and technical support. Contact us to discuss your requirements and to obtain a quote for purchasing this critical pharmaceutical intermediate.