For chemists and researchers in diverse fields, identifying versatile and reliable chemical intermediates is key to unlocking new synthesis pathways and developing innovative products. 2-Hydroxyphenylacetic Acid (CAS 614-75-5) is a compound that embodies this versatility, serving as a crucial building block in both the pharmaceutical and agrochemical industries, as well as in broader organic chemistry applications.

The Chemical Profile of 2-Hydroxyphenylacetic Acid

Characterized by its molecular formula C8H8O3 and molecular weight of 152.15, 2-Hydroxyphenylacetic Acid typically appears as a yellow crystal powder with a purity often specified at ≥98%. Its chemical structure features a phenolic hydroxyl group and a carboxylic acid group, positioned strategically on an aromatic ring. This dual functionality makes it highly reactive and adaptable for a range of chemical transformations, including esterification, etherification, amidation, and condensation reactions. Its solubility in polar solvents like methanol and water further enhances its utility in various reaction media.

Key Applications Driving Demand

The demand for 2-Hydroxyphenylacetic Acid is largely driven by its indispensable role in the synthesis of high-value end products:

  • Agrochemical Sector: It is a fundamental intermediate in the production of azoxystrobin, a leading broad-spectrum fungicide widely used to protect crops from various diseases. The efficacy and market penetration of azoxystrobin underscore the importance of a consistent supply of its precursor.
  • Pharmaceutical Sector: The compound is also vital for the synthesis of active pharmaceutical ingredients (APIs), notably atenolol, a beta-blocker used to treat hypertension and other cardiovascular conditions. The reliability of this intermediate directly impacts the production of essential medicines.
  • Research and Development: Beyond these major applications, 2-Hydroxyphenylacetic Acid serves as a valuable reagent for chemists exploring novel synthetic routes, developing new materials, or researching metabolic pathways.

Sourcing and Supplier Reliability

Procurement professionals and R&D scientists seeking to purchase 2-Hydroxyphenylacetic Acid need to partner with dependable manufacturers and suppliers. Factors such as guaranteed purity (≥98%), competitive pricing, consistent supply, and comprehensive documentation (like COAs and SDS) are paramount. Manufacturers based in regions like China, equipped with advanced synthesis capabilities, often offer these advantages. When you look to buy this chemical, engaging with a supplier that understands your technical requirements and can provide responsive support is key. We are committed to being that trusted supplier, ensuring you have access to high-quality 2-Hydroxyphenylacetic Acid for your synthesis needs.

In summary, 2-Hydroxyphenylacetic Acid is a cornerstone intermediate in modern chemical synthesis, enabling the production of critical pharmaceuticals and agrochemicals. Its versatile chemical nature and the increasing demand for its end-products highlight its ongoing importance in the chemical industry.