Understanding the properties and applications of key chemical intermediates is vital for any chemist or procurement specialist. 2-Iodopyridine (CAS: 5029-67-4) is a compound that offers significant utility in the field of organic synthesis. This article delves into its chemical and physical characteristics, as well as its diverse applications, providing insights for potential buyers and researchers.

Chemical Profile of 2-Iodopyridine

2-Iodopyridine is a halogenated pyridine derivative with the molecular formula C5H4IN. Its molecular weight is approximately 204.996 g/mol. Physically, it is often described as a light yellow liquid. Key specifications to note for procurement include its purity, typically specified as an assay of ≥97.0%, and its boiling point, around 215.4 °C at 760 mmHg, with a density of 2.0±0.1 g/cm³. The presence of the iodine atom on the pyridine ring makes it a highly reactive compound, particularly amenable to various synthetic transformations that are foundational in modern chemistry.

Key Properties and Reactivity:

  • Halogen Reactivity: The iodine substituent is an excellent leaving group, facilitating nucleophilic substitution reactions.
  • Coupling Reactions: 2-Iodopyridine is a preferred substrate for transition-metal catalyzed cross-coupling reactions, such as Suzuki, Heck, and Sonogashira couplings, enabling the formation of complex carbon-carbon bonds.
  • Versatility: It serves as a versatile scaffold for introducing the pyridine ring into larger, more complex molecules.

Applications in Organic Synthesis

The reactivity profile of 2-Iodopyridine translates into broad applications across several scientific disciplines:

  • Pharmaceutical Intermediates: It is a cornerstone in the synthesis of numerous APIs. The pyridine nucleus is a common structural motif in many drugs, and 2-Iodopyridine provides an efficient route to incorporate it. Buyers looking to purchase this compound for drug development will find its predictable reactions invaluable.
  • Agrochemical Development: The compound is used in the creation of pesticides, herbicides, and other crop protection agents, contributing to enhanced agricultural productivity.
  • Materials Science: Its derivatives can find applications in the synthesis of functional materials, including organic electronic components.
  • Research & Development: Academic and industrial R&D labs frequently utilize 2-Iodopyridine for exploring new synthetic routes and discovering novel chemical entities.

Sourcing High-Quality 2-Iodopyridine

For those requiring this essential chemical intermediate, sourcing from a reliable manufacturer is critical. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier committed to providing high-purity 2-Iodopyridine with a guaranteed assay of ≥97.0%. We offer competitive pricing and ensure consistent product availability for both research quantities and bulk industrial orders. Our expertise in custom synthesis and contract manufacturing makes us an ideal partner for all your chemical needs. If you are looking to buy 2-Iodopyridine or inquire about its price, please contact our sales team for prompt assistance.