The pharmaceutical industry constantly seeks efficient and reliable intermediates to drive drug discovery and development. Among these, 2-Iodopyridine (CAS: 5029-67-4) holds significant importance as a versatile building block. For procurement specialists and R&D chemists, understanding its applications and how to source it effectively is crucial for project success.

2-Iodopyridine: A Cornerstone in Pharmaceutical Synthesis

2-Iodopyridine is a heterocyclic compound characterized by its pyridine ring substituted with an iodine atom at the 2-position. Its chemical formula is C5H4IN, with a molecular weight of 204.996 g/mol. The compound's physical properties, such as its appearance as a light yellow liquid and an assay of ≥97.0%, highlight its suitability for demanding synthetic procedures. Its primary value lies in its reactivity, enabling chemists to introduce the pyridine scaffold into complex molecular architectures. This is particularly vital in the synthesis of many Active Pharmaceutical Ingredients (APIs), where pyridine rings are common pharmacophores contributing to drug efficacy and targeting.

Key Synthesis Applications in Pharma:

  • Coupling Reactions: 2-Iodopyridine is an excellent substrate for various cross-coupling reactions, including Suzuki, Stille, and Sonogashira couplings. These reactions are fundamental for forming carbon-carbon and carbon-heteroatom bonds, essential for assembling drug molecules.
  • Nucleophilic Substitution: The iodine atom can be readily displaced by various nucleophiles, allowing for functionalization of the pyridine ring and the creation of diverse chemical entities.
  • Intermediate for API Synthesis: It serves as a precursor for a wide range of APIs targeting various therapeutic areas, from oncology to cardiovascular diseases.

Procurement Strategy for 2-Iodopyridine

When sourcing 2-Iodopyridine for pharmaceutical applications, buyers must prioritize quality and reliability. NINGBO INNO PHARMCHEM CO.,LTD. offers robust solutions for these needs:

  • High Purity: We guarantee a minimum assay of ≥97.0%, ensuring that our 2-Iodopyridine meets the stringent purity requirements of pharmaceutical R&D and manufacturing.
  • Reliable Supply: As a dedicated manufacturer, we maintain consistent stock and offer flexible bulk supply options to meet project demands, from laboratory scale to industrial production.
  • Competitive Pricing: Our efficient manufacturing processes and direct supply model enable us to offer competitive prices, making essential intermediates more accessible. We encourage potential clients to inquire about pricing and bulk discounts.
  • Technical Documentation: We provide comprehensive documentation, including COAs and MSDS, to support your quality assurance and safety protocols.

For procurement managers and research scientists looking to buy 2-Iodopyridine, partnering with a trusted supplier like NINGBO INNO PHARMCHEM CO.,LTD. is a strategic advantage. Our commitment to quality, coupled with our extensive manufacturing experience, ensures you receive a product that drives your pharmaceutical innovation forward. Contact us today to discuss your requirements and secure your supply of this vital chemical intermediate.