In the pharmaceutical industry, the quality of chemical intermediates directly impacts the efficacy and safety of the final drug product. For 3-Chloro-1-propanol (CAS 627-30-5), a vital intermediate, understanding its purity and specifications is paramount for procurement managers and R&D scientists. This article delves into the critical parameters to consider when buying this compound and highlights the importance of sourcing from reliable manufacturers.

3-Chloro-1-propanol, a colorless liquid, is primarily valued for its role in synthesizing Active Pharmaceutical Ingredients (APIs). The most critical specification is its assay, which typically needs to be ≥99%. A high assay ensures that the compound is primarily 3-Chloro-1-propanol, with minimal contamination from other isomers or related substances. Manufacturers often report the single impurity limit, which should ideally be ≤0.3%, further guaranteeing the compound's purity. Low moisture content (≤0.2%) is also a key factor, as water can interfere with certain organic reactions.

When evaluating suppliers, requesting a detailed Certificate of Analysis (CoA) for 3-Chloro-1-propanol is standard practice. This document outlines the actual test results for parameters such as appearance, assay, moisture, and specific impurities. Comparing CoAs from different manufacturers can help identify those who consistently meet or exceed industry standards. For procurement professionals looking to buy this intermediate, prioritizing suppliers who provide comprehensive and accurate documentation is essential for compliance and quality control.

The chemical properties of 3-Chloro-1-propanol, such as its boiling point (around 165°C) and density (around 1.1 g/cm³), are also important for process chemists to consider during reaction design and scale-up. Refractive index and flash point data are also typically included in product specifications. These physical properties, along with chemical purity, contribute to the overall quality and usability of the intermediate in pharmaceutical manufacturing processes. We ensure all our products meet stringent quality controls.

In conclusion, for any pharmaceutical application requiring 3-Chloro-1-propanol (CAS 627-30-5), meticulous attention to purity and specifications is non-negotiable. By partnering with trusted manufacturers and thoroughly reviewing product documentation, buyers can ensure they are obtaining a high-quality intermediate that meets the demanding requirements of the pharmaceutical industry. Contact us to learn more about our product quality and how we can support your procurement needs.