The constant pursuit of effective treatments for chronic diseases like diabetes drives innovation in pharmaceutical chemistry. At the core of many successful drug syntheses lie crucial chemical intermediates, such as 3-Ethyl-4-methyl-3-pyrrolin-2-one (CAS 766-36-9). This compound is a pivotal building block in the manufacturing process of Glimepiride, a widely prescribed medication that helps patients manage their blood glucose levels. Understanding the significance of this intermediate, its properties, and how to procure it reliably is essential for pharmaceutical companies and researchers.

The Chemical Foundation: Properties of 3-Ethyl-4-methyl-3-pyrrolin-2-one

3-Ethyl-4-methyl-3-pyrrolin-2-one, with the molecular formula C7H11NO and a molecular weight of 125.17, is a heterocyclic organic compound. It belongs to the class of alpha,beta-unsaturated lactams. Typically appearing as a white to off-white crystalline powder, it possesses a melting point in the range of 100-104°C. Its stability and reactivity profile make it highly suitable for complex organic synthesis reactions. The compound's slight solubility in water and common organic solvents like methanol and chloroform aids in its handling and processing during manufacturing. For those looking to buy this chemical, these properties are important considerations for laboratory and production use.

From Intermediate to Innovation: Applications in Pharmaceuticals

The primary and most recognized application of 3-Ethyl-4-methyl-3-pyrrolin-2-one is its role as a key intermediate in the synthesis of Glimepiride. Glimepiride functions by enhancing insulin secretion and improving insulin sensitivity, making it a cornerstone therapy for type 2 diabetes. The precise chemical structure of 3-Ethyl-4-methyl-3-pyrrolin-2-one is integral to constructing the Glimepiride molecule efficiently and with high purity. This ensures that the final drug product is safe and effective for patient use. As a result, a consistent and high-quality supply of this intermediate is critical for pharmaceutical manufacturers. Inquiring about the price from reputable suppliers is a crucial step in ensuring uninterrupted production.

Sourcing Strategy: Partnering with Expert Suppliers

For pharmaceutical companies, sourcing critical intermediates like 3-Ethyl-4-methyl-3-pyrrolin-2-one (CAS 766-36-9) requires a strategic approach. Partnering with experienced chemical manufacturers, particularly those based in China with established expertise in fine chemical synthesis, offers distinct advantages. These suppliers can provide:

  • High-purity products (>98%) essential for pharmaceutical applications.
  • Scalable manufacturing to meet varying demand, from R&D to commercial volumes.
  • Competitive pricing due to optimized production processes and economies of scale.
  • Reliable supply chains and logistical support for global distribution.
We are a dedicated manufacturer committed to providing high-quality chemical intermediates. We invite you to contact us to learn more about our 3-Ethyl-4-methyl-3-pyrrolin-2-one and to obtain a competitive quote for your pharmaceutical synthesis needs.