In the realm of fine chemicals, certain compounds stand out for their versatility and importance in various industrial and research applications. 3-Ethyl-4-methyl-3-pyrrolin-2-one, identified by its CAS Registry Number 766-36-9, is one such molecule. This five-membered alpha,beta-unsaturated lactam derivative has found significant utility, particularly as a pharmaceutical intermediate. This article aims to provide a detailed understanding of its chemical characteristics, synthesis pathways, and the advantages of procuring it from reliable suppliers.

Chemical Profile of 3-Ethyl-4-methyl-3-pyrrolin-2-one

3-Ethyl-4-methyl-3-pyrrolin-2-one (C7H11NO) is characterized by its lactam ring structure, featuring an ethyl group at the 3-position and a methyl group at the 4-position. Its molecular weight is approximately 125.17 g/mol. The compound typically presents as a white to almost white crystalline powder, with a melting point range often cited around 100-104°C. Its solubility profile indicates slight solubility in water and polar organic solvents like methanol and chloroform. The stability of this compound under various conditions, including heat and light, makes it a practical choice for chemical synthesis.

Synthesis and Manufacturing of CAS 766-36-9

The synthesis of 3-Ethyl-4-methyl-3-pyrrolin-2-one can be achieved through several chemical routes. Common starting materials include ethyl acetoacetate and allylamine derivatives. Palladium(II)-assisted cyclization and ring-closing metathesis strategies are among the established methods for its preparation. Manufacturers focus on optimizing these processes to ensure high yields, purity, and cost-effectiveness. For businesses looking to buy this chemical, working with a dedicated chemical manufacturer in China offers access to these advanced production techniques and economies of scale. This ensures a stable supply for both research and industrial applications.

Applications and Industrial Relevance

The primary application of 3-Ethyl-4-methyl-3-pyrrolin-2-one is its role as an intermediate in the pharmaceutical industry. It is a crucial component in the synthesis of Glimepiride, an antidiabetic agent. Beyond this specific use, its heterocyclic structure and functional groups make it an attractive molecule for further exploration in medicinal chemistry. Researchers may utilize it as a building block for developing new therapeutic compounds targeting various diseases. For companies in need of this chemical, understanding its properties and applications is key to efficient procurement. Enquiring about price and availability from manufacturers is the first step towards integrating it into your research or production workflows.

Sourcing and Procurement Considerations

When sourcing 3-Ethyl-4-methyl-3-pyrrolin-2-one (CAS 766-36-9), it is vital to partner with a reputable supplier. Key factors to consider include product purity (typically 98% or higher), consistency of quality batch after batch, and reliable delivery. Manufacturers in China are well-equipped to supply this intermediate in various quantities, from grams for research purposes to metric tons for large-scale industrial production. Engaging with a manufacturer directly can provide the best value and ensure a secure supply chain. We invite you to contact us to inquire about the price and to explore how we can meet your requirements for this versatile chemical intermediate.