In the intricate world of chemical synthesis, specific compounds emerge as indispensable building blocks, driving innovation across various industries. Among these, 3-Methoxyacetophenone, identified by its CAS number 586-37-8, stands out as a crucial aromatic ketone. Its unique chemical structure and reactivity make it a highly sought-after intermediate, particularly within the pharmaceutical and fine chemical sectors. Understanding its properties and applications is key for researchers and procurement managers looking to secure a reliable supply chain.

The Chemical Profile of 3-Methoxyacetophenone

Also known by synonyms such as 1-(3-methoxyphenyl)ethanone, 3-acetylanisole, or m-methoxyacetophenone, this compound features a methoxy group (-OCH3) positioned meta to the acetyl group on the phenyl ring. This specific arrangement imbues the molecule with distinct characteristics, making it amenable to a range of chemical transformations. Its molecular formula is C9H10O2, and it typically presents as a clear to pale-yellow liquid, with a purity often exceeding 99% by GC, a testament to its quality as a fine chemical.

Applications Driving Demand

The versatility of 3-Methoxyacetophenone fuels its demand across several high-value applications:

  • Pharmaceutical Intermediates: One of the primary uses of 3-Methoxyacetophenone is as a precursor in the synthesis of Active Pharmaceutical Ingredients (APIs). It serves as a foundational structure for various drugs, including nonsteroidal anti-inflammatory drugs (NSAIDs) and compounds targeting the central nervous system (CNS). Researchers actively seek this intermediate to develop new therapeutic agents. If you are looking to buy 3-methoxyacetophenone for your pharmaceutical R&D, partnering with a reputable manufacturer in China is crucial for obtaining high-purity material at competitive prices.
  • Organic Synthesis: Beyond pharmaceuticals, its reactive nature makes it valuable in broader organic synthesis. The meta-positioned methoxy group influences electrophilic substitution and carbonyl-based reactions, enabling chemists to construct complex molecular architectures.
  • Flavors and Fragrances: Possessing a characteristic aromatic odor, 3-Methoxyacetophenone finds application as a component in the formulation of perfumes and certain food products, contributing unique olfactory and gustatory profiles.
  • Photoinitiator Precursors: In the realm of material science, it acts as a precursor for photoinitiators used in UV-curable coatings, inks, and adhesives. This application is vital for industries requiring fast curing and durable finishes.

Sourcing and Procurement Considerations

For businesses and research institutions, securing a consistent and high-quality supply of 3-Methoxyacetophenone is paramount. When sourcing this chemical, it is advisable to work with established suppliers and manufacturers who can provide detailed product specifications, certificates of analysis (CoA), and reliable logistics. Understanding the market for this intermediate, including current pricing trends and availability from key suppliers, can significantly impact your procurement strategy. If you are seeking a dependable 1-(3-methoxyphenyl)ethanone supplier, exploring options from leading chemical hubs like China offers access to competitive prices and a broad range of product grades.

In conclusion, 3-Methoxyacetophenone (CAS 586-37-8) is a vital chemical intermediate whose significance continues to grow. Its extensive applications in pharmaceuticals, organic synthesis, and other specialty fields underscore its importance. By understanding its properties and engaging with trusted manufacturers and suppliers, you can effectively leverage this compound to advance your research and production goals.