In the realm of synthetic chemistry, specific molecules serve as versatile linchpins, enabling the creation of a vast array of complex compounds. 1-(3-Methoxyphenyl)ethanone, commonly identified by its CAS number 586-37-8 and known by its IUPAC name, is one such critical intermediate. This aromatic ketone, also referred to as 3-methoxyacetophenone or 3-acetylanisole, plays a pivotal role in various synthesis pathways, particularly within the pharmaceutical industry and advanced organic chemistry. For professionals looking to buy 1-(3-methoxyphenyl)ethanone, understanding its reactivity and application spectrum is key to leveraging its full potential.

Chemical Reactivity and Structural Significance

The molecular structure of 1-(3-Methoxyphenyl)ethanone features an acetyl group attached to a benzene ring, which is further substituted with a methoxy group at the meta position. This specific arrangement is crucial for its synthetic utility. The electron-donating methoxy group influences the electron density of the aromatic ring, directing electrophilic substitution reactions and modulating the reactivity of the carbonyl group. This makes it an excellent starting material for a variety of transformations, including:

  • Electrophilic Aromatic Substitution: The presence of the methoxy group activates the ortho and para positions relative to it, allowing for controlled introduction of substituents onto the aromatic ring.
  • Carbonyl Chemistry: The ketone functionality can undergo numerous reactions, such as reduction, oxidation, nucleophilic addition, and condensation reactions, forming diverse functional groups.

Key Applications in Synthesis

The versatility of 1-(3-Methoxyphenyl)ethanone translates into significant applications across multiple sectors:

  • Pharmaceutical Synthesis: As a key pharmaceutical intermediate, this compound is instrumental in the synthesis of Active Pharmaceutical Ingredients (APIs). It serves as a building block for drugs targeting various conditions, including inflammatory diseases and neurological disorders. Researchers frequently seek this compound from reliable manufacturers to ensure the purity and efficacy of their drug candidates. If you are involved in drug discovery, securing a stable supply of high-purity CAS 586-37-8 is essential.
  • Organic Synthesis and Fine Chemicals: Beyond pharmaceuticals, it is a valuable reagent in academic and industrial organic synthesis laboratories. Its structure is incorporated into more complex molecules used in agrochemicals, specialized polymers, and advanced materials. Sourcing from a reputable supplier ensures you receive material that meets strict specifications for these applications.
  • Flavor and Fragrance Industry: The aromatic nature of 1-(3-Methoxyphenyl)ethanone makes it useful in the creation of specific scents and flavor profiles, contributing to its demand in the consumer goods sector.
  • Material Science: It can also function as a precursor for photoinitiators, vital components in UV-curable coatings and inks, enabling rapid and efficient curing processes.

Procuring 1-(3-Methoxyphenyl)ethanone

When looking to procure this vital chemical, prioritizing suppliers who offer high purity (e.g., >99% GC) and provide detailed technical documentation is crucial. Many businesses choose to buy 3-methoxyacetophenone from manufacturers in China due to competitive prices and significant production capacities. However, it is always recommended to conduct due diligence on potential partners to ensure quality, reliability, and adherence to international standards. A dependable supplier will offer excellent customer service and efficient logistics to meet your project timelines.

In summary, 1-(3-Methoxyphenyl)ethanone (CAS 586-37-8) is an indispensable tool for synthetic chemists. Its diverse applications and unique reactivity underscore its importance as a fundamental building block in modern chemical industries.