In the dynamic field of research and development, access to high-quality, versatile chemical intermediates is fundamental. 4-Acetoxyindole (CAS 5585-96-6) stands out as a compound of significant interest due to its utility in organic synthesis and its role in creating valuable research compounds. This article delves into the properties, applications, and sourcing considerations for 4-Acetoxyindole, guiding researchers and procurement specialists on how to effectively buy this important chemical.

The Chemical Profile of 4-Acetoxyindole

4-Acetoxyindole, also referred to as 1H-indol-4-yl acetate, presents as an off-white solid. Its chemical structure, C10H9NO2, provides a foundational framework for various synthetic pathways. With a molecular weight of 175.18, it possesses physical characteristics such as a melting point between 100-102°C and a density of 1.255 g/cm³. Crucially for R&D applications, it is typically supplied with a purity of ≥98.0%, ensuring a high degree of reliability in synthetic reactions. The low water content, usually ≤0.5%, further enhances its stability and suitability for sensitive chemical processes.

Unlocking Synthesis Potential: Key Applications

The primary significance of 4-Acetoxyindole lies in its role as a precursor for the synthesis of Psilocine and related compounds. Psilocine, a naturally occurring psychedelic compound, and its structural analogues are subjects of ongoing research, particularly in neurochemistry and the development of potential therapeutic interventions. Researchers utilize 4-Acetoxyindole as a key building block to construct these complex molecular architectures, facilitating the exploration of new chemical entities with varied pharmacological profiles. Its versatility extends to general organic synthesis, where its indole core can be functionalized to create a range of specialty chemicals.

Procurement: Finding Reliable Suppliers for Purchase

For scientists and procurement managers, the ability to reliably buy 4-Acetoxyindole is critical for uninterrupted research. Identifying trustworthy suppliers is the first step. Reputable chemical suppliers offer detailed product specifications, safety data, and efficient logistics. When looking to purchase this intermediate, consider factors such as purity verification, packaging options, and delivery timelines. Many leading suppliers are located in China, known for its robust chemical manufacturing sector, offering competitive pricing and accessibility. Engaging with established manufacturers ensures that you are acquiring a product that meets stringent quality standards.

Economic and Strategic Buying Considerations

When evaluating the cost of 4-Acetoxyindole, buyers should consider not only the per-gram price but also the overall value proposition. This includes the assurance of quality, consistency in supply, and responsive customer service. For larger research projects or ongoing production needs, purchasing in bulk quantities from a manufacturer can significantly reduce the per-unit cost. It is always recommended to request a formal quote to understand the exact pricing, including any applicable discounts for volume purchases. Building a relationship with a supplier who understands your specific research needs can lead to more favorable terms and a more streamlined procurement process.

In summary, 4-Acetoxyindole is a vital intermediate for researchers involved in organic synthesis and the exploration of compounds like Psilocine. By understanding its properties and prioritizing reliable sourcing from established suppliers and manufacturers, R&D professionals can effectively acquire this compound to drive their scientific endeavors forward.