For researchers and procurement managers in the chemical and pharmaceutical sectors, sourcing high-quality intermediates is paramount. One such critical compound is 4-Acetoxyindole, identified by its CAS number 5585-96-6. This article serves as a guide for buyers looking to purchase this essential organic synthesis intermediate, focusing on purity, application, and reliable sourcing from manufacturers and suppliers, particularly those based in China.

Understanding 4-Acetoxyindole

4-Acetoxyindole, also known by synonyms such as 1H-indol-4-yl acetate, is characterized by its off-white solid appearance. Its molecular formula is C10H9NO2, with a molecular weight of 175.18400. The compound boasts a high purity level, typically exceeding 98.0%, and a low water content, generally not more than 0.5%. These specifications are crucial for its primary application: serving as a key intermediate in the organic synthesis of Psilocine and its various analogues. Its melting point of 100-102°C and a density of 1.255 g/cm³ further define its physical properties.

Why Purity Matters for Your Synthesis Needs

When engaging in complex organic synthesis, the purity of starting materials and intermediates directly impacts reaction yields, product quality, and the efficiency of purification processes. For applications involving the synthesis of Psilocine and its derivatives, where structural integrity and specific biological activity are key, using a high-purity 4-Acetoxyindole is non-negotiable. Impurities can lead to unwanted side reactions, the formation of by-products, and can complicate downstream processing, ultimately increasing costs and extending project timelines. Therefore, buyers should always prioritize obtaining this compound from reputable manufacturers who can provide certificates of analysis detailing purity and other critical parameters.

Key Applications and the Need for Reliable Suppliers

The primary utility of 4-Acetoxyindole lies in its role as a precursor in the synthesis of Psilocine, a well-known psychoactive compound, and its related analogues. These analogues are often synthesized for research purposes, including pharmacological studies and the development of potential new therapeutic agents. Beyond this specific application, it can also serve as a versatile building block in broader fine chemical synthesis. For R&D scientists and product formulators, securing a consistent supply of this intermediate is vital for ongoing research and development efforts. This is where identifying reliable suppliers and manufacturers becomes crucial.

Sourcing Strategies: Finding a Manufacturer and Supplier in China

China has emerged as a global hub for chemical manufacturing, offering a vast array of intermediates at competitive price points. For 4-Acetoxyindole, identifying a trusted Chinese manufacturer or supplier is key to a successful procurement strategy. Buyers should look for companies that not only offer competitive pricing but also demonstrate a commitment to quality control and timely delivery. When you buy 4-acetoxyindole from a reputable source, you gain access to detailed product specifications, safety data sheets (SDS), and often, customized packaging and delivery options. Engaging directly with manufacturers often allows for better price negotiation, especially for bulk orders, and can provide greater transparency into the production process.

Price and Purchasing Considerations

The price of 4-Acetoxyindole can vary based on purity, quantity, and the specific supplier. For bulk purchases, buyers can expect more favorable pricing structures. It is advisable to request detailed quotes from multiple suppliers to compare offers. When discussing price, also consider lead times, shipping costs, and any minimum order quantities. For companies seeking to buy 4-acetoxyindole, establishing a long-term relationship with a dependable supplier can ensure a stable supply chain for critical research and production needs.

In conclusion, for any organization requiring high-purity 4-Acetoxyindole for organic synthesis, particularly in the realm of Psilocine analogue development, careful supplier selection is essential. Focusing on quality, reliable sourcing from manufacturers in China, and competitive pricing will ensure the success of your chemical projects.