4-Amino-2-fluorobenzonitrile (CAS 53312-80-4): Properties, Synthesis, and Industrial Significance
NINGBO INNO PHARMCHEM CO., LTD. is a leading supplier of specialized chemical intermediates that are fundamental to advancing scientific research and industrial production. Among our key offerings is 4-Amino-2-fluorobenzonitrile (CAS 53312-80-4), a highly versatile compound that serves as a critical intermediate in organic synthesis, particularly for the pharmaceutical and agrochemical sectors.
The chemical structure of 4-Amino-2-fluorobenzonitrile, featuring an amino group and a fluorine atom on a benzonitrile ring, endows it with unique reactivity and stability. This makes it an invaluable building block for creating complex organic molecules. Typically presented as an off-white to yellow powder, it has a molecular formula of C7H5FN2 and a molecular weight of 136.13. Its physical characteristics, including a density of approximately 1.3 g/cm³, a boiling point of 288.2 °C, and a flash point of 128.1 °C, underscore its robustness in various chemical applications. The compound's low vapor pressure indicates minimal volatility, ensuring its stability during handling and processing.
The foremost application of 4-Amino-2-fluorobenzonitrile is its role as an organic synthesis intermediate. In the pharmaceutical realm, it is crucial for synthesizing fluorinated pharmaceuticals. The incorporation of fluorine atoms can significantly boost a drug's efficacy, improve metabolic stability, and enhance bioavailability. This makes 4-Amino-2-fluorobenzonitrile a vital component in the development of innovative medicinal compounds. Furthermore, it is widely utilized in the agrochemical industry to produce advanced crop protection agents, contributing to more efficient and sustainable agricultural practices. The compound’s dual functional groups—amino and nitrile—allow for extensive chemical modifications, offering broad synthetic possibilities.
The manufacturing of 4-Amino-2-fluorobenzonitrile requires sophisticated synthesis techniques to achieve the high purity levels (≥98.0%) essential for its intended applications. Manufacturers, particularly those in China, have made significant advancements in optimizing production processes to meet the growing global demand. For companies aiming for consistent quality and supply chain reliability, partnering with a reputable 4-Amino-2-fluorobenzonitrile manufacturer is a critical step.
Proper storage conditions are vital for maintaining the quality and reactivity of 4-Amino-2-fluorobenzonitrile. It is recommended to store the compound in a cool, dry, and well-ventilated area, away from direct sunlight and oxidizing agents. Standard laboratory safety practices, including the use of personal protective equipment, should always be followed during handling. Packaging is typically offered in 25 kg drums, with options for customization to suit diverse client needs. The consistent availability of high-quality 4-Amino-2-fluorobenzonitrile is crucial for advancing chemical research and industrial production.
NINGBO INNO PHARMCHEM CO., LTD. is your reliable partner for high-purity 4-Amino-2-fluorobenzonitrile and a comprehensive range of custom synthesis services. If you are looking to buy 4-Amino-2-fluorobenzonitrile or require specialized chemical solutions, please contact us. We are committed to delivering exceptional products and expert support to facilitate your research and development initiatives.
Perspectives & Insights
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