The Role of 4-Amino-2-fluorobenzonitrile as a Versatile Organic Synthesis Intermediate
NINGBO INNO PHARMCHEM CO., LTD. specializes in providing essential chemical intermediates that drive innovation across various sectors. Among these is 4-Amino-2-fluorobenzonitrile (CAS 53312-80-4), a compound recognized for its significant utility in organic synthesis. This article highlights its key attributes and applications, emphasizing why it is a valuable asset for chemical R&D and production.
4-Amino-2-fluorobenzonitrile is a finely tuned molecule characterized by its benzonitrile core functionalized with an amino group and a fluorine atom. This structural arrangement makes it a potent intermediate for building more complex organic structures. Typically appearing as an off-white to yellow powder, it possesses a molecular formula of C7H5FN2, with a molecular weight of 136.13. Its physical properties, such as a density of 1.3 g/cm³ and a high boiling point of 288.2 °C, indicate its suitability for various chemical reactions that may involve elevated temperatures. The compound's stability is further supported by its low vapor pressure, ensuring reliable performance during synthesis.
The primary utility of 4-Amino-2-fluorobenzonitrile lies in its extensive application as an intermediate in organic synthesis. In the pharmaceutical industry, it is crucial for the development of fluorinated pharmaceuticals, which often exhibit enhanced pharmacological profiles, including improved metabolic stability and increased bioavailability. This makes it a sought-after compound for drug discovery and development. Similarly, the agrochemical sector leverages its versatility to create advanced crop protection agents, contributing to more effective and sustainable agricultural practices. The compound's reactive functional groups—the nitrile and the amino group—allow for a wide spectrum of chemical transformations, making it a highly adaptable building block.
The production of 4-Amino-2-fluorobenzonitrile requires stringent quality control to achieve high purity levels, often exceeding 98.0%. This precision is vital for its use in synthesizing sensitive molecules where impurities can significantly impact the outcome. Manufacturers in China have developed advanced synthesis routes and scaled up production to meet the growing global demand. For companies seeking a dependable supply of this critical intermediate, identifying a reputable 4-Amino-2-fluorobenzonitrile supplier is a strategic decision that ensures product quality and operational continuity.
Effective storage and handling are paramount to preserving the quality of 4-Amino-2-fluorobenzonitrile. Recommendations include storing it in a cool, dry, and well-ventilated environment, away from direct sunlight and oxidizing agents. Standard safety protocols for handling chemical powders should be observed. Packaging is often available in 25 kg drums, with options for customization to meet diverse client needs. The compound’s market presence is robust, driven by its essential role in key chemical industries. As an important organic synthesis intermediate, its availability is key to ongoing innovation.
NINGBO INNO PHARMCHEM CO., LTD. is your trusted partner for high-quality 4-Amino-2-fluorobenzonitrile and other fine chemical intermediates. We also provide custom synthesis services, leveraging our extensive experience in complex chemical reactions. If you are interested in buying 4-Amino-2-fluorobenzonitrile or exploring our custom synthesis capabilities, please contact us. Our commitment is to deliver exceptional chemical solutions tailored to your specific project requirements.
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