The development of effective cancer therapies relies heavily on the availability of high-quality chemical building blocks. For manufacturers producing advanced oncology drugs, intermediates like 4-Amino-3-iodopyrazolo[3,4-d]pyrimidine (CAS: 151266-23-8) are fundamental. This compound is a key component in the synthesis of Ibrutinib, a targeted therapy that has revolutionized the treatment of certain blood cancers. As a specialized manufacturer, we understand the critical importance of this intermediate in the pharmaceutical value chain.

The Role of 4-Amino-3-iodopyrazolo[3,4-d]pyrimidine in Oncology Drug Manufacturing

4-Amino-3-iodopyrazolo[3,4-d]pyrimidine is a heterocyclic compound characterized by its pyrazolopyrimidine core, functionalized with an amino and an iodine group. This specific chemical structure makes it an ideal precursor for constructing the complex molecular framework of Ibrutinib. The precise regiochemistry and purity of this intermediate are crucial for the successful synthesis of the API. Pharmaceutical companies looking to buy 4-Amino-3-iodopyrazolo[3,4-d]pyrimidine must ensure they source from manufacturers with stringent quality control processes.

Key Specifications and Sourcing Strategies:

  • Purity and Assay: A high assay (e.g., ≥99.0% by HPLC) is essential for efficient and reproducible synthesis. When you purchase 4-Amino-3-iodopyrazolo[3,4-d]pyrimidine, always verify the purity specifications provided by the supplier.
  • Appearance and Physical Properties: Typically appearing as an off-white to light brown powder, its physical form is important for handling and processing.
  • Manufacturer Reputation: Identifying a reliable 4-Amino-3-iodopyrazolo[3,4-d]pyrimidine manufacturer is key to securing a stable supply chain. Companies with ISO or GMP certifications often indicate a commitment to quality. We are a trusted Ibrutinib intermediate supplier with a focus on global pharmaceutical needs.
  • Cost and Availability: Understanding the prevailing price of 4-Amino-3-iodopyrazolo[3,4-d]pyrimidine and ensuring consistent availability are important for cost management and production scheduling. Requesting quotes from several suppliers is a standard practice.

Empowering Drug Development

Our mission as a chemical manufacturer is to support the advancement of oncology treatments by providing essential, high-quality intermediates. We are committed to being a leading provider of 4-Amino-3-iodopyrazolo[3,4-d]pyrimidine, ensuring that R&D scientists and pharmaceutical manufacturers have access to the materials they need. For companies seeking to purchase this critical intermediate, partnering with experienced and quality-driven suppliers is the path to successful drug synthesis and development.