The efficacy of chemical synthesis relies heavily on understanding the intrinsic properties of the intermediates used. For 4-Amino-5-bromo-2-chloropyrimidine (CAS: 205672-25-9), its specific physical and chemical characteristics are what make it an invaluable asset in the laboratories of organic chemists, pharmaceutical developers, and agrochemical formulators. As a leading supplier of fine chemicals, we are committed to providing detailed information on our products to empower our clients. Here, we delve into the key properties of 4-Amino-5-bromo-2-chloropyrimidine and explain why they are crucial for its diverse applications.

Physical Appearance and State

Our 4-Amino-5-bromo-2-chloropyrimidine is described as a clear brown to purple liquid. This visual characteristic is important for initial quality assessment, indicating the product's homogeneity and physical form. While it is commonly referred to as a liquid, its melting point is noted between 187-188 °C in certain solvents, suggesting a complex phase behavior or high-purity solid state at standard room temperature. However, for practical handling and storage in its supplied form, its liquid state is key.

Critical Chemical Specifications

The utility of 4-Amino-5-bromo-2-chloropyrimidine in synthesis is dictated by its chemical specifications:

  • Assay (Purity): A minimum assay of ≥98% is standard, ensuring that the compound is sufficiently pure for its intended applications in pharmaceutical and agrochemical synthesis, minimizing side reactions and guaranteeing product integrity.
  • Molecular Formula and Weight: C4H3BrClN3 and 208.44 g/mol are fundamental identifiers for stoichiometric calculations and reaction planning.
  • CAS Number: 205672-25-9 is the unique identifier, critical for regulatory compliance, literature searches, and unambiguous procurement.
  • Boiling Point: Approximately 369.8 ± 22.0 °C. This high boiling point indicates thermal stability under many reaction conditions.
  • Density: Approximately 1.960 ± 0.06 g/cm³. This value is useful for volumetric calculations and understanding the substance's physical handling characteristics.
  • Water Solubility: Slightly soluble in water. This property influences solvent choices for reactions and purification steps, often requiring organic solvents or mixtures for effective dissolution.
  • Storage Conditions: Recommended storage at 2–8 °C under an inert atmosphere (like nitrogen or argon) is vital for maintaining its stability and purity over time, protecting it from degradation.

Why These Properties Matter for Buyers

For chemists looking to buy 4-Amino-5-bromo-2-chloropyrimidine, these properties directly impact synthesis planning, reaction optimization, and cost-effectiveness. Understanding the purity level assures the success of downstream reactions. Knowledge of solubility and boiling points aids in selecting appropriate solvents and reaction temperatures. Proper storage recommendations ensure that the chemical maintains its quality from our facility to yours. As a manufacturer and supplier in China, we ensure these specifications are met through rigorous quality control, providing you with the confidence needed to integrate this intermediate into your most demanding synthetic projects.

When you need to purchase chemical intermediates, partnering with a supplier that clearly communicates these essential properties is key. We are committed to providing high-quality 4-Amino-5-bromo-2-chloropyrimidine that meets exacting standards. We invite you to contact us to learn more about its specifications and how we can support your chemical synthesis needs.