For organic chemists and researchers, the availability of versatile and reactive building blocks is key to unlocking new synthetic pathways and creating novel compounds. 4-Amino-5-bromo-2-chloropyrimidine (CAS: 205672-25-9) stands out as a particularly valuable intermediate in the realm of organic synthesis. Its unique structural features—a pyrimidine ring substituted with amine, bromine, and chlorine groups—endow it with a reactivity profile that makes it indispensable for a wide range of chemical transformations. As a dedicated manufacturer and supplier of fine organic chemicals, we provide researchers and industrial chemists with access to this essential compound, facilitating advancements in various scientific disciplines.

Chemical Properties and Synthetic Potential

4-Amino-5-bromo-2-chloropyrimidine is characterized by its clear brown to purple liquid appearance and its key properties, including a melting point of 187-188 °C and a boiling point around 369.8 °C. Its molecular formula, C4H3BrClN3, and molecular weight of 208.44 g/mol further define its chemical identity. The presence of the bromine atom allows for facile participation in cross-coupling reactions, such as Suzuki, Sonogashira, and Buchwald-Hartwig couplings, which are cornerstones of modern organic synthesis for forming new carbon-carbon and carbon-heteroatom bonds. The amino group can be modified through acylation, alkylation, or used in condensation reactions, while the chlorine atom offers opportunities for nucleophilic substitution or further cross-coupling. This trifunctional nature makes it an exceptionally versatile scaffold for building molecular complexity.

Applications Across Disciplines

The utility of 4-Amino-5-bromo-2-chloropyrimidine extends beyond academic research into industrial applications:

  • Pharmaceutical Intermediates: It serves as a crucial intermediate in the synthesis of numerous pharmaceutical compounds, including potential drug candidates for various therapeutic areas. Its pyrimidine core is a common feature in many bioactive molecules.
  • Agrochemicals: The compound is also employed in the development of agrochemicals, contributing to the creation of new herbicides, insecticides, and fungicides designed to improve crop yields and protection.
  • Materials Science: In some instances, such heterocyclic compounds find applications in the development of functional materials, such as organic semiconductors or dyes, although its primary roles are in life sciences.

Procuring from a Reliable Supplier in China

For chemists and purchasing managers seeking to buy 4-Amino-5-bromo-2-chloropyrimidine, selecting a reputable supplier is paramount. As a leading manufacturer and supplier based in China, we offer this intermediate with a guaranteed purity of ≥98%. Our production processes are optimized for efficiency and quality, ensuring that you receive a product that meets the highest standards for your synthetic endeavors. We understand the critical nature of timely delivery and consistent quality for research and industrial projects. By partnering with us, you benefit from competitive pricing, robust supply chain management, and the expertise of a company deeply involved in the fine chemical industry. We are your reliable source to purchase chemical intermediates that drive scientific advancement.

In conclusion, 4-Amino-5-bromo-2-chloropyrimidine is a testament to the power of well-designed chemical intermediates in advancing organic synthesis. Its rich reactivity and broad applicability make it a sought-after compound for chemists across various fields. We invite you to explore our offerings and discover how our high-quality 4-Amino-5-bromo-2-chloropyrimidine can contribute to the success of your next synthesis project.