The intricate function of the kidneys is vital for overall health, and precise diagnostic tools are essential for their evaluation. 4-Aminohippuric Acid (CAS 61-78-9), often abbreviated as PAH, is a cornerstone compound in nephrology, renowned for its application in measuring renal plasma flow (RPF). For researchers and medical professionals seeking a reliable supplier of this crucial diagnostic aid, understanding its properties and sourcing effectively is key.

The Gold Standard for Renal Plasma Flow Measurement

PAH possesses unique characteristics that make it the benchmark for assessing kidney function. It is efficiently filtered by the glomeruli and actively secreted by the renal tubules, with minimal reabsorption. This nearly complete extraction from the blood during a single pass through the kidneys allows for a highly accurate calculation of effective renal plasma flow. When administered intravenously, the rate at which PAH is cleared from the bloodstream provides invaluable data about the kidney's blood processing capacity.

Clinical Significance and Diagnostic Utility

The use of 4-Aminohippuric Acid in clinical settings directly aids in the diagnosis and management of various kidney disorders. By quantifying RPF, clinicians can identify conditions that impair kidney blood supply or filtration efficiency. This makes it an indispensable tool in patient assessment, particularly for those with suspected or known renal dysfunction. Professionals looking to buy 4-Aminohippuric Acid for diagnostic purposes require consistent purity and reliable supply to ensure the accuracy and reproducibility of their tests.

Research Applications in Nephrology and Pharmacology

Beyond its diagnostic role, 4-Aminohippuric Acid is a critical research tool. It serves as a model substrate for studying the function and inhibition of organic anion transporters (OATs), which play a significant role in the secretion of drugs and toxins by the kidneys. Researchers utilize PAH in laboratory settings to investigate drug interactions, understand drug metabolism, and develop novel therapies for renal diseases. As a vital component in these studies, sourcing high-quality PAH from reputable manufacturers is essential for obtaining credible results.

Procuring High-Quality 4-Aminohippuric Acid

When you need to purchase 4-Aminohippuric Acid, partnering with a trusted supplier based in China offers distinct advantages. We pride ourselves on being a leading manufacturer and exporter of this critical pharmaceutical intermediate. Our commitment to stringent quality control ensures that every batch of 4-Aminohippuric Acid (CAS 61-78-9) meets high purity standards, crucial for both diagnostic accuracy and research integrity. We offer competitive prices and efficient logistical solutions for global distribution. Contact us today to secure a reliable supply of this essential compound for your diagnostic and research endeavors.