In the intricate world of pharmaceutical development, the quality and availability of chemical intermediates are critical drivers of progress. 4-Bromo-2-fluoroacetanilide, known by its CAS number 326-66-9, stands out as a particularly valuable building block, widely utilized by researchers and manufacturers in the synthesis of Active Pharmaceutical Ingredients (APIs).

The strategic placement of a bromine atom and a fluorine atom on the aromatic ring of 4-Bromo-2-fluoroacetanilide provides chemists with significant synthetic flexibility. The bromine atom serves as a convenient handle for various cross-coupling reactions, such as palladium-catalyzed Suzuki, Stille, or Heck reactions, allowing for the introduction of diverse carbon frameworks. Concurrently, the fluorine atom can profoundly influence the electronic properties and metabolic stability of the resulting drug molecules, often leading to improved efficacy and pharmacokinetic profiles.

Many pharmaceutical companies and contract research organizations (CROs) actively purchase this intermediate to construct complex drug candidates targeting a wide range of therapeutic areas. The ability to reliably source high-purity 4-Bromo-2-fluoroacetanilide is therefore essential. Reputable suppliers, particularly those based in China, often provide material with purity levels exceeding 99%, essential for minimizing by-products and ensuring the integrity of the synthesized APIs.

When considering the price and procurement of this compound, direct engagement with a primary manufacturer is often the most advantageous route. This not only secures competitive pricing but also offers greater assurance of consistent quality and supply chain transparency. The availability of standard packaging like 25kg drums and the capacity for custom orders further support large-scale API production.

Researchers involved in drug discovery will find that the unique reactivity of 4-Bromo-2-fluoroacetanilide makes it an indispensable tool. Its successful integration into synthesis schemes can accelerate the development timeline for new medicines. Therefore, identifying and partnering with a trustworthy supplier for this crucial intermediate is a key step for any pharmaceutical development team aiming for efficient and high-quality API manufacturing.