For chemists and researchers working with 4-Bromo-2-fluoroacetanilide (CAS 326-66-9), a thorough understanding of its physical and chemical properties, along with its safety profile, is fundamental for effective and safe handling. This intermediate is a key component in many synthetic pathways, and knowing its characteristics helps optimize its use.

Physically, 4-Bromo-2-fluoroacetanilide typically presents as a light beige to white or light yellow amorphous powder. Its melting point is generally reported in the range of 156-157°C, indicating it is a stable solid at room temperature. The molecular formula is C8H7BrFNO, with a molecular weight of approximately 232.05 g/mol. These details are critical for chemists when planning reactions and ensuring accurate stoichiometry.

Chemically, the compound features an acetamide group attached to a fluorinated and brominated benzene ring. This structure makes it amenable to various reactions. The bromine atom can be readily substituted or involved in metal-catalyzed cross-coupling reactions, while the fluorine atom influences electron density and can impact the reactivity of the aromatic ring and the overall properties of derived molecules. Many laboratories and industrial facilities purchase this intermediate for its versatility in organic synthesis.

Safety considerations are paramount when handling any chemical. 4-Bromo-2-fluoroacetanilide is classified with hazard statements such as H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Therefore, appropriate personal protective equipment (PPE) is essential. This includes wearing chemical-resistant gloves, safety goggles or face shields, and working in a well-ventilated area or fume hood to avoid inhalation of dust.

When looking to buy this chemical, it's important to source it from a reputable manufacturer or supplier who provides a detailed Safety Data Sheet (SDS). This document outlines all necessary safety precautions, first-aid measures, and handling procedures. Engaging with a trusted supplier ensures you receive not only a high-quality product but also the necessary information for its safe application.

Understanding these properties and safety guidelines empowers researchers and procurement specialists to use 4-Bromo-2-fluoroacetanilide effectively and responsibly in their synthetic endeavors, ensuring both successful outcomes and a safe working environment.