In the intricate world of pharmaceutical manufacturing, the selection of raw materials and intermediates is a critical decision that influences the efficacy, safety, and cost of the final drug product. 4-Hydroxybenzaldehyde, identified by its CAS number 123-08-0, stands out as a pivotal intermediate, particularly in the synthesis of Ezetimibe, a widely prescribed medication for cholesterol management. For purchasing managers and R&D scientists seeking a reliable source, understanding the product's attributes and identifying a trustworthy supplier is paramount.

The Role of 4-Hydroxybenzaldehyde in Pharmaceutical Synthesis

4-Hydroxybenzaldehyde is an organic compound that serves as a fundamental building block in various chemical synthesis pathways. Its aldehyde and phenol functional groups make it a versatile reactant. In the pharmaceutical sector, its most significant application is as a key precursor in the multi-step synthesis of Ezetimibe. The successful production of Ezetimibe hinges on the quality and consistent availability of 4-Hydroxybenzaldehyde. This necessitates sourcing from manufacturers who can guarantee high purity, typically assaying at ≥99.5%, and maintaining strict control over residual moisture and other potential contaminants.

Key Considerations When You Buy 4-Hydroxybenzaldehyde

When evaluating your options to purchase 4-Hydroxybenzaldehyde, consider these critical factors:

  • Purity and Specifications: Always verify the assay (≥99.5%), appearance (light yellow crystalline powder), melting point (112-116 °C), and moisture content (≤0.5%). These specifications are vital for ensuring successful reaction kinetics and API quality.
  • Supplier Reliability: Partner with a manufacturer that has a proven track record in supplying pharmaceutical intermediates. Look for consistent product quality, dependable delivery schedules, and a commitment to customer service. Suppliers based in China often offer competitive pricing due to manufacturing efficiencies.
  • Regulatory Compliance: Ensure the supplier can provide necessary documentation to support your regulatory filings, such as Certificates of Analysis (CoA) and details on manufacturing practices.
  • Supply Chain Stability: A stable supply chain is crucial for uninterrupted production. Choosing a manufacturer with robust production capacity and a strong logistical network minimizes the risk of supply disruptions.

Finding a Trusted 4-Hydroxybenzaldehyde Manufacturer in China

China has become a global hub for chemical manufacturing, offering a wide array of suppliers for pharmaceutical intermediates. To identify the best partner, focus on companies that:

  • Demonstrate a deep understanding of pharmaceutical industry requirements.
  • Invest in advanced quality control systems and maintain high production standards.
  • Offer competitive pricing without compromising on product quality.
  • Provide excellent customer support and technical assistance.

By carefully considering these aspects, you can secure a reliable supply of 4-Hydroxybenzaldehyde (CAS 123-08-0), a foundational ingredient for your pharmaceutical manufacturing needs. As a dedicated manufacturer, we are committed to being your trusted source for this essential chemical intermediate, ensuring quality and value for your operations.