4-Nitrophthalic Acid: A Key Organic Synthesis Intermediate
The realm of organic synthesis relies heavily on versatile chemical intermediates that can be readily transformed into complex molecules. Among these, 4-Nitrophthalic Acid, identified by its CAS number 610-27-5 and molecular formula C8H5NO6, stands out for its broad applicability. This compound serves as a foundational element in various chemical processes, particularly within the pharmaceutical and dye industries. Understanding its properties and synthetic utility is crucial for chemists and formulators seeking to innovate and optimize their production.
As a key organic synthesis intermediate, 4-Nitrophthalic Acid offers unique chemical reactivity due to the presence of both nitro and dicarboxylic acid functional groups on a benzene ring. This structural characteristic allows for a wide range of chemical transformations, including reduction of the nitro group to an amine, esterification of the carboxylic acids, and other substitution reactions. These capabilities make it an invaluable precursor for creating more complex molecular architectures that are essential for drug development and the synthesis of specialized dyes.
In the pharmaceutical sector, 4-Nitrophthalic Acid plays a significant role as an impurity or intermediate in the synthesis of various active pharmaceutical ingredients (APIs). For instance, it is noted in the production pathways of drugs like Apremilast, highlighting its importance in ensuring the purity and efficacy of final pharmaceutical products. For R&D scientists and procurement managers looking to buy 4-Nitrophthalic Acid for pharmaceutical applications, ensuring a high purity grade (typically ≥98%) is paramount to avoid downstream processing issues and meet regulatory standards. Sourcing from a reliable 4-Nitrophthalic Acid manufacturer in China, such as NINGBO INNO PHARMCHEM CO.,LTD., can provide the necessary quality assurance.
Beyond pharmaceuticals, 4-Nitrophthalic Acid is also a critical component in the synthesis of dyes and pigments. Its structure lends itself to the creation of colored compounds with specific lightfastness and chromatic properties, essential for textiles, printing inks, and imaging technologies. The compound's ability to undergo reactions that form chromophores makes it a valuable asset for dye manufacturers seeking to develop new shades or improve existing formulations. Companies seeking a consistent supply for dye production will find the availability and quality from established suppliers highly beneficial.
For those in the market to purchase 4-Nitrophthalic Acid, understanding its physical properties is also important. Typically appearing as a yellow to beige crystalline powder, with a melting point around 159-161°C, its handling and storage require standard chemical safety protocols. As a leading 4-Nitrophthalic Acid supplier, we emphasize providing products that meet stringent specifications, supporting diverse chemical synthesis needs effectively.
In summary, 4-Nitrophthalic Acid (CAS 610-27-5) is more than just a chemical compound; it is an enabler of innovation in critical industries. Its role as an organic synthesis intermediate, particularly in pharmaceuticals and dyes, underscores its importance. Businesses looking to secure a reliable supply of this compound should consider working with experienced manufacturers who can guarantee quality and consistent availability.
Perspectives & Insights
Nano Explorer 01
“This compound serves as a foundational element in various chemical processes, particularly within the pharmaceutical and dye industries.”
Data Catalyst One
“Understanding its properties and synthetic utility is crucial for chemists and formulators seeking to innovate and optimize their production.”
Chem Thinker Labs
“As a key organic synthesis intermediate, 4-Nitrophthalic Acid offers unique chemical reactivity due to the presence of both nitro and dicarboxylic acid functional groups on a benzene ring.”