For professionals in the chemical industry, a thorough understanding of key intermediates is fundamental. 4-Nitrophthalic Acid (CAS 610-27-5), a compound with the molecular formula C8H5NO6, is one such intermediate, integral to various synthesis processes. This article aims to provide a detailed overview of its properties, essential safety considerations, and guidance on sourcing this vital chemical effectively. Whether you are a researcher, formulator, or procurement specialist, grasping these aspects will enhance your operational efficiency and product development.

The chemical and physical properties of 4-Nitrophthalic Acid are critical for its application. Typically presented as a yellow to beige crystalline powder, it possesses a molecular weight of 211.13 g/mol and a melting point in the range of 159-161°C. These characteristics influence how it is handled, stored, and incorporated into reaction schemes. Its utility as an organic synthesis intermediate is derived from its dual functionality: the nitro group and the two carboxylic acid groups, which allow for a wide array of chemical transformations. This makes it a sought-after component in the manufacturing of pharmaceuticals and dyes.

Safety and handling are paramount when working with any chemical intermediate. 4-Nitrophthalic Acid, while a valuable compound, requires adherence to safety protocols. It can be an irritant to the skin, eyes, and respiratory system. Therefore, when handling this compound, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, protective clothing, and eye protection. Proper ventilation in the workspace is also recommended. In case of accidental exposure, immediate rinsing with ample water and seeking medical advice are important steps. Storage recommendations typically involve keeping the compound in a clean, dry, and cool place, away from direct sunlight and incompatible materials like strong oxidizing agents and bases, to maintain its stability and prevent hazardous reactions.

Sourcing 4-Nitrophthalic Acid requires careful consideration of suppliers. When you search to buy 4-Nitrophthalic Acid, you’ll encounter numerous manufacturers and suppliers, especially in China, which is a major hub for chemical production. It is advisable to partner with established 4-Nitrophthalic Acid suppliers who can demonstrate consistent product quality, such as specifying a minimum assay of ≥98%. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are known for their commitment to quality and reliability, offering high-grade intermediates that meet international standards. Seeking out suppliers who provide detailed technical data sheets, certificates of analysis, and responsive customer service will ensure a smoother procurement process.

Ultimately, understanding the comprehensive profile of 4-Nitrophthalic Acid—from its chemical behavior and physical attributes to safe handling procedures and reliable sourcing channels—empowers professionals to utilize it effectively. Whether for pharmaceutical intermediates or advanced dye synthesis, a well-informed approach to acquiring this compound will contribute to successful outcomes and innovation.