5-Aminoisophthalic Acid: A Key Intermediate in Pharmaceutical Synthesis
The pharmaceutical industry relies heavily on a diverse range of chemical intermediates to synthesize life-saving drugs and diagnostic agents. Among these crucial compounds, 5-Aminoisophthalic Acid (CAS 99-31-0) holds significant importance, particularly as a precursor for advanced pharmaceutical ingredients and contrast agents used in medical imaging. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated pharmaceutical intermediate supplier, recognizes the critical nature of this compound and its reliable provision to the global market.
5-Aminoisophthalic Acid is a versatile organic molecule characterized by its benzene ring substituted with two carboxylic acid groups and one amino group. This unique structural arrangement makes it an ideal building block for complex organic synthesis. Its application in the pharmaceutical sector is a testament to its chemical stability, reactivity, and ability to be functionalized into highly specific therapeutic or diagnostic molecules.
The Role in Contrast Agent Synthesis
One of the most prominent pharmaceutical applications of 5-Aminoisophthalic Acid is in the synthesis of Iohexol. Iohexol is a non-ionic X-ray contrast medium widely used in medical imaging procedures such as CT scans and angiography. The synthesis of Iohexol involves several steps, with 5-Aminoisophthalic Acid serving as a foundational component. Its structure contributes to the overall stability and efficacy of the contrast agent, enabling clearer visualization of internal bodily structures and aiding in accurate diagnosis.
For pharmaceutical companies involved in the production of Iohexol or other similar contrast agents, securing a consistent and high-quality supply of 5-aminoisophthalic acid is paramount. The purity of this intermediate directly influences the quality and safety of the final drug product. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. ensure that their product meets the stringent requirements of the pharmaceutical industry, often with assay purity exceeding 97%.
Beyond Contrast Agents: Broader Pharmaceutical Applications
While its role in Iohexol synthesis is a key application, 5-Aminoisophthalic Acid is also valuable in other areas of pharmaceutical research and development:
- Drug Discovery: As a versatile building block, it can be incorporated into novel molecular scaffolds for the discovery of new therapeutic agents. Its functional groups allow for diverse chemical modifications, exploring new drug candidates.
- Synthesis of Complex APIs: The compound's structure lends itself to the creation of more complex Active Pharmaceutical Ingredients (APIs) through multi-step organic synthesis.
- Materials for Drug Delivery: In some research contexts, derivatives of 5-Aminoisophthalic Acid might be explored for use in specialized drug delivery systems due to their potential for controlled release or targeted delivery.
Choosing a Reliable Supplier
When sourcing CAS 99-31-0 for pharmaceutical applications, it is crucial to partner with a reputable manufacturer. Factors to consider include:
- Purity and Consistency: Verify the assay purity and consistency across batches.
- Documentation: Ensure availability of Certificates of Analysis (CoA) and other relevant quality documents.
- Manufacturing Standards: Enquire about the manufacturing environment and quality control processes.
- Supply Chain Reliability: Confirm the supplier's capacity to meet demand and their logistical capabilities.
In summary, 5-Aminoisophthalic Acid is far more than just a chemical reagent; it is a foundational component in the development of vital pharmaceutical products. Its reliable supply by experienced manufacturers is essential for advancing healthcare and diagnostics.
Perspectives & Insights
Bio Analyst 88
“Synthesis of Complex APIs: The compound's structure lends itself to the creation of more complex Active Pharmaceutical Ingredients (APIs) through multi-step organic synthesis.”
Nano Seeker Pro
“Materials for Drug Delivery: In some research contexts, derivatives of 5-Aminoisophthalic Acid might be explored for use in specialized drug delivery systems due to their potential for controlled release or targeted delivery.”
Data Reader 7
“Choosing a Reliable Supplier When sourcing CAS 99-31-0 for pharmaceutical applications, it is crucial to partner with a reputable manufacturer.”