In the realm of advanced organic synthesis, having access to versatile and reactive intermediates is key to innovation. 5-Bromoindoline (CAS 22190-33-6) has emerged as a compound of significant interest for chemists engaged in complex molecular construction. This article explores the chemical characteristics, synthesis pathways, and broad application spectrum of 5-Bromoindoline, underscoring its importance for researchers and industrial chemists alike. We also highlight how to efficiently purchase this compound from reliable manufacturers.

Chemical Profile of 5-Bromoindoline

5-Bromoindoline, also known by its IUPAC name 5-bromo-2,3-dihydro-1H-indole, is a heterocyclic organic compound with the molecular formula C8H8BrN. Its molecular weight is 198.06 g/mol. Typically presented as a solid with a low melting point, its most crucial feature is the bromine atom at the 5-position. This bromine substituent acts as an excellent leaving group and a reactive site, readily participating in various carbon-carbon and carbon-heteroatom bond-forming reactions, particularly palladium-catalyzed cross-coupling reactions.

Efficient Synthesis of 5-Bromoindoline

The synthesis of 5-Bromoindoline is well-documented, with common routes involving the preparation and subsequent deprotection of protected indoline derivatives. A prevalent method involves the hydrolysis of 1-acetyl-5-bromoindoline. This synthetic strategy ensures the production of a high-purity intermediate, which is essential for sensitive downstream reactions. When you buy 5-Bromoindoline from a quality supplier, you are benefiting from optimized synthesis protocols.

Broad Application Spectrum

The versatility of 5-Bromoindoline makes it valuable across several scientific disciplines:

  • Pharmaceuticals: It's a foundational intermediate in the synthesis of numerous APIs, contributing to the development of new therapeutic agents.
  • Agrochemicals: Its structural motif can be incorporated into new pesticide or herbicide formulations.
  • Materials Science: Researchers utilize it for creating novel polymers and electronic materials, leveraging its unique reactivity.
  • Research and Development: As a building block, it enables exploration of structure-activity relationships and the discovery of new chemical entities.

For those looking to leverage these applications, securing a dependable supply of 5-Bromoindoline is paramount. As a leading chemical manufacturer and supplier, we offer CAS 22190-33-6 with guaranteed quality and competitive pricing. We encourage you to get a quote and discuss your specific requirements for this vital intermediate. Our commitment is to support your scientific and industrial endeavors with reliable chemical solutions from China.