In the realm of specialized chemicals, 5-Chloropyrazine-2-Carbohydrazide, identified by CAS number 848952-83-0, stands out as a valuable intermediate for various synthetic applications. As a leading chemical manufacturer and supplier based in China, we are dedicated to providing researchers and industries with high-quality compounds, including this important pyrazine derivative. This article outlines its synthesis, key uses, and the benefits of sourcing it from a trusted partner.

Understanding 5-Chloropyrazine-2-Carbohydrazide

5-Chloropyrazine-2-Carbohydrazide is a heterocyclic organic compound with the molecular formula C5H5ClN4O. Its structure features a pyrazine ring substituted with a chlorine atom at the 5-position and a carbohydrazide group at the 2-position. This arrangement of functional groups imparts unique reactivity, making it a sought-after building block in organic synthesis. Typically presenting as an off-white crystalline powder, it has a molecular weight of approximately 172.57 g/mol. Its density is noted around 1.496 g/cm³, and a refractive index of 1.607.

The Synthesis Pathway and Quality Assurance

The production of 5-Chloropyrazine-2-Carbohydrazide commonly begins with methyl 5-chloropyrazine-2-carboxylate. This precursor is reacted with hydrazine monohydrate, often in methanol, under reflux conditions for several hours. The resulting precipitate is then collected and dried. Our manufacturing processes are optimized to ensure efficient synthesis and high yields. Crucially, stringent quality control measures are implemented throughout the production cycle. We provide comprehensive product characterization data, including 1H NMR, elemental analysis, and mass spectral data, to verify purity and identity, ensuring that customers receive a product that meets their precise specifications when they buy.

Applications Across Industries

The versatility of 5-Chloropyrazine-2-Carbohydrazide makes it valuable in several key areas:

  • Pharmaceutical Synthesis: It serves as a critical intermediate for the synthesis of Active Pharmaceutical Ingredients (APIs) and complex drug molecules. Its heterocyclic nature is often leveraged for its potential biological activity.
  • Organic Chemistry Research: This compound is widely used by researchers exploring new synthetic methodologies and creating novel organic compounds.
  • Material Science: In some instances, heterocyclic derivatives find applications in advanced materials, though its primary use remains in life sciences.

Choosing a Reliable Supplier

When you need to source 5-Chloropyrazine-2-Carbohydrazide, selecting a reliable manufacturer and supplier is paramount. As a direct supplier from China, we offer competitive pricing, consistent quality, and responsive customer service. We understand the importance of a stable supply chain for your research and production needs. Whether you are looking for small quantities for laboratory research or bulk orders for industrial applications, we are equipped to meet your demands. Inquire about our custom synthesis services for specific requirements.

Partner with us for your chemical sourcing needs and experience the advantages of working with a dedicated manufacturer committed to excellence.