In the intricate field of organic chemistry and pharmaceutical development, specific chemical intermediates play pivotal roles in enabling the creation of complex molecules. 5-Chloropyrazine-2-Carbohydrazide, identified by its CAS number 848952-83-0, is one such compound. As a specialized chemical supplier, we provide detailed information on this important intermediate, covering its chemical properties, synthesis, and applications, to aid researchers and procurement specialists.

Chemical Profile of 5-Chloropyrazine-2-Carbohydrazide

5-Chloropyrazine-2-Carbohydrazide is a derivative of pyrazine, characterized by the molecular formula C5H5ClN4O and a molecular weight of 172.57 g/mol. Its structure includes a pyrazine ring with a chlorine substituent and a carbohydrazide group, which are key to its reactivity in various chemical transformations. The compound typically presents as an off-white crystalline powder, with reported physical properties including a density of 1.496 g/cm³ and a refractive index of 1.607. These characteristics are important for handling and processing in laboratory and industrial settings.

Synthesis and Manufacturing Process

The synthesis of 5-Chloropyrazine-2-Carbohydrazide is a well-documented process in chemical literature and patents. A common method involves the reaction of methyl 5-chloropyrazine-2-carboxylate with hydrazine monohydrate. This reaction is typically carried out in a suitable solvent, such as methanol, and often requires heating to reflux for an extended period to ensure complete conversion. Upon completion, the product is isolated through filtration and drying. Our manufacturing partners adhere to strict protocols to guarantee consistent product quality and purity, often exceeding 95%. This meticulous synthesis process is vital for producing an intermediate suitable for demanding applications in pharmaceutical research and development.

Key Applications and Research Use

The primary utility of 5-Chloropyrazine-2-Carbohydrazide lies in its role as a versatile building block in organic synthesis. Its bifunctional nature allows it to participate in a range of reactions, making it invaluable for:

  • Pharmaceutical Synthesis: It is frequently used as an intermediate in the creation of novel pharmaceutical compounds and active pharmaceutical ingredients (APIs). The pyrazine scaffold is present in many drugs targeting various diseases.
  • Medicinal Chemistry: Researchers employ this compound to synthesize analogues and explore structure-activity relationships, a fundamental process in drug discovery.
  • Agrochemical Research: Similar heterocyclic structures also find applications in the development of pesticides and other agricultural chemicals.

Sourcing High-Quality Intermediates

For researchers and companies looking to buy 5-Chloropyrazine-2-Carbohydrazide, it is essential to source from a reliable manufacturer and supplier. We provide this critical chemical with guaranteed quality, backed by comprehensive analytical data. Our commitment extends to offering competitive pricing, custom synthesis services, and a stable supply chain, ensuring your R&D projects proceed without interruption. Inquire with us for quotes and further details on purchasing this key intermediate.