In the intricate world of chemical synthesis, precise specifications and a reliable supply chain are critical for success. 5-Fluoro-2-hydroxybenzonitrile (CAS: 91407-41-9) is a key intermediate widely recognized for its utility in pharmaceuticals and fine chemicals. This article provides a comprehensive overview of its typical specifications and offers guidance on sourcing this essential compound from China, targeting procurement managers and R&D scientists.

Understanding the Specifications of 5-Fluoro-2-hydroxybenzonitrile

When evaluating 5-Fluoro-2-hydroxybenzonitrile for your applications, paying close attention to its chemical and physical properties is paramount. While specific requirements may vary slightly between suppliers, common specifications often include:

  • Chemical Name: 5-Fluoro-2-hydroxybenzonitrile
  • CAS Number: 91407-41-9
  • Molecular Formula: C7H4FNO
  • Molecular Weight: Approximately 137.11 g/mol
  • Appearance: Typically a solid, often described as a white or off-white powder.
  • Purity: High purity is essential, with most reputable manufacturers offering assays of 97% or higher. Gas Chromatography (GC) or High-Performance Liquid Chromatography (HPLC) are commonly used methods for purity determination.
  • Storage Conditions: Generally recommended to be stored at room temperature in a dry, well-ventilated area, often under an inert atmosphere to maintain stability.

Understanding these specifications is the first step for any procurement specialist looking to buy 5-Fluoro-2-hydroxybenzonitrile that meets project requirements.

Strategic Sourcing from China Manufacturers

China has become a global hub for chemical manufacturing, offering a vast network of suppliers for essential intermediates like 5-Fluoro-2-hydroxybenzonitrile. To navigate this market effectively and secure the best CAS 91407-41-9 price, consider the following:

  • Identify Reputable Manufacturers: Look for companies with established production facilities and a strong presence in the fine chemical or pharmaceutical intermediate market. Platforms that list verified suppliers and offer customer reviews can be helpful.
  • Request Samples and Documentation: Always request a free sample for initial quality assessment and obtain the Certificate of Analysis (CoA) and Material Safety Data Sheet (MSDS). This documentation is vital for R&D and safety compliance.
  • Evaluate Supplier Reliability: Consider the supplier's experience, customer service, and ability to provide consistent product quality. A proactive 5-Fluoro-2-hydroxybenzonitrile supplier will be responsive to inquiries and transparent about their processes.
  • Negotiate for Bulk Orders: If your needs are substantial, negotiating pricing for larger quantities can lead to significant cost savings. Discuss your projected usage with potential suppliers to explore volume discounts.

Applications in Synthesis

The chemical structure of 5-Fluoro-2-hydroxybenzonitrile makes it a valuable intermediate for synthesizing a wide range of complex organic molecules, including active pharmaceutical ingredients (APIs), agrochemicals, and specialty chemicals. Its application in various coupling reactions and functional group transformations is well-documented in chemical literature, underscoring its importance for researchers in organic synthesis.

Conclusion

Securing high-quality 5-Fluoro-2-hydroxybenzonitrile requires a strategic approach to sourcing. By understanding its key specifications and diligently evaluating Chinese manufacturers and suppliers, procurement professionals can ensure they obtain a reliable, high-purity intermediate that supports their critical research and production needs.