In the realm of fine chemicals and synthesis, certain compounds emerge as indispensable building blocks due to their unique reactivity and versatility. 5-Fluoro-2-methylbenzonitrile, identified by CAS number 77532-79-7, is one such critical intermediate. This article explores its chemical nature, its broad range of applications, and the advantages of sourcing it from a reliable chemical manufacturer and supplier.

Understanding the Chemical Structure and Properties

5-Fluoro-2-methylbenzonitrile is an aromatic organic compound with the molecular formula C8H6FN. Its structure features a benzonitrile core substituted with a fluorine atom at the 5-position and a methyl group at the 2-position. This specific arrangement of functional groups endows the molecule with valuable reactivity. The nitrile group (-C≡N) is a highly useful synthetic handle, capable of undergoing various transformations such as reduction to amines, hydrolysis to carboxylic acids, or participation in cycloaddition reactions. The fluorine atom often enhances lipophilicity, metabolic stability, and binding interactions in larger molecules, making it a sought-after feature in pharmaceuticals and advanced materials. Typically supplied as an off-white crystalline powder with a purity of ≥99.0%, it meets the stringent requirements for precise chemical synthesis.

Versatile Applications Across Industries

The utility of 5-Fluoro-2-methylbenzonitrile spans across several key industries:

  • Pharmaceutical Intermediates: This is perhaps its most prominent application. It serves as a crucial precursor for synthesizing a wide array of Active Pharmaceutical Ingredients (APIs). The unique combination of fluorine and nitrile functionalities allows chemists to build complex drug structures efficiently, contributing to the development of new therapeutic agents.
  • Agrochemicals: Similar to pharmaceuticals, fluorinated compounds are often incorporated into pesticides and herbicides to improve their efficacy, stability, and targeted action.
  • Specialty Chemicals: Beyond pharmaceuticals and agrochemicals, this intermediate can be used in the development of advanced materials, electronic chemicals, or specialized polymers where specific chemical and physical properties are required.
  • Research and Development: In academic and industrial research laboratories, 5-Fluoro-2-methylbenzonitrile is a valuable tool for exploring new synthetic methodologies and discovering novel compounds.

Sourcing Strategies: Quality, Price, and Reliability

When you need to buy 5-Fluoro-2-methylbenzonitrile, especially for commercial production or critical research, choosing the right supplier is paramount. Factors to consider include:

  • Purity: Ensure the supplier guarantees a high purity level, typically above 98% or 99%, backed by a Certificate of Analysis (COA).
  • Price: Competitive pricing is essential. Manufacturers based in China, like NINGBO INNO PHARMCHEM CO.,LTD., often offer cost-effective solutions for bulk quantities.
  • Reliability: A dependable supply chain, consistent product quality, and timely delivery are critical to avoid production disruptions.
  • Technical Support: A good supplier will offer technical assistance and readily provide safety documentation like MSDS.

By diligently evaluating these factors, R&D professionals and procurement managers can secure a consistent supply of this vital chemical building block, enabling advancements in their respective fields. For any requirement of 5-Fluoro-2-methylbenzonitrile CAS 77532-79-7, partnering with an experienced chemical manufacturer and supplier is key to success.